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Ação da via de sinalização Hippo durante o reconhecimento materno da gestação em ovelhas após balanço energético negativo induzido
(Universidade Federal de Santa MariaBrasilMedicina VeterináriaUFSMPrograma de Pós-Graduação em Medicina VeterináriaCentro de Ciências Rurais, 2021-02-25)
The initial period of pregnancy is very critical for the occurrence of early embryonic losses and failures in maternal-fetal communication and often occurs under a negative energy balance (NEB), which can affect negatively ...
ANKHD1, a novel component of the Hippo signaling pathway, promotes YAP1 activation and cell cycle progression in prostate cancer cells
(Elsevier B.V., 2014-06-10)
ANKHD1 is a multiple ankyrin repeat containing protein, recently identified as a novel member of the Hippo signaling pathway. the present study aimed to investigate the role of ANKHDI in DU145 and LNCaP prostate cancer ...
Fator de crescimento de fibroblasto 18 (FGF18) modula a expressão de CTGF em CCOs e embriões bovinos produzidos in vitro
(Universidade Federal de Santa MariaBrasilMedicina VeterináriaUFSMPrograma de Pós-Graduação em Medicina VeterináriaCentro de Ciências Rurais, 2021-03-01)
In 1995, the Hippo pathway was initially discovered in Drosophila melanogaster, and
since then several researchers have been trying to better understand this pathway. The Hippo
pathway is involved in cell proliferation ...
The YAP/TAZ Signaling Pathway in the Tumor Microenvironment and Carcinogenesis: Current Knowledge and Therapeutic Promises
(MDPI, 2022)
The yes-associated protein (YAP) and the transcriptional coactivator with PDZ-binding motif (TAZ) are transcriptional coactivators, members of the Hippo signaling pathway, which play a critical role in cell growth regulation, ...
Fator de crescimento fibroblástico 18 (FGF18) modula a expressão de genes da via de sinalização hippo em células da granulosa bovina
(Universidade Federal de Santa MariaBrasilMedicina VeterináriaUFSMPrograma de Pós-Graduação em Medicina VeterináriaCentro de Ciências Rurais, 2023-03-28)
Proliferation, functional differentiation and morphological transformation of granulosa cells (GCs) are events that occur for ovarian follicular development, achieved, atresia and ovulation. There is evidence to show that ...
Activation of skeletal muscle FAPs by LPA requires the Hippo signaling via the FAK pathway
(2023-05)
Lysophosphatidic acid (LPA) is a lysophospholipid that signals through six G-protein coupled receptors (LPARs), LPA1 to LPA6. LPA has been described as a potent modulator of fibrosis in different pathologies. In skeletal ...
Influência da via hippo em carcinomas de células escamosas de língua oral
(Universidade Federal do Rio Grande do NorteBrasilUFRNPROGRAMA DE PÓS-GRADUAÇÃO EM CIÊNCIAS ODONTOLÓGICAS, 2023)
Leukaemia Inhibitory Factor (LIF) inhibits cancer stem cells tumorigenic properties through hippo kinases activation in gastric cancer
(2020)
Cancer stem cells (CSCs) present chemo-resistance mechanisms contributing to tumour
maintenance and recurrence, making their targeting of utmost importance in gastric cancer (GC)
therapy. The Hippo pathway has been ...