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Effect of gonadotropin-releasing hormone agonist and antagonist on proliferation and apoptosis of human luteinized granulosa cells
(Elsevier, 2006-04)
The GnRH agonist leuprolide acetate (LA) inhibited DNA synthesis in epidermal growth factor-stimulated human granulosa luteinized cell cultures. This effect was blocked by the prior addition of a GnRH antagonist antide ...
Activation of Cl Channels by Human Chorionic Gonadotropin in Luteinized Granulosa Cells of the Human Ovary Modulates Progesterone Biosynthesis
(ENDOCRINE SOC, 2008-09)
Chloride permeability pathways and progesterone (P4) secretion
elicited by human chorionic gonadotropin (hCG) in
human granulosa cells were studied by electrophysiological
techniques and single-cell volume, membrane ...
Relationship of different ovarian stimulation response with vascular endothelial growth factor and degree of granulosa cell apoptosis.
(Oxford University Press, 2001-09-01)
The aim of this study was to evaluate the concentration of vascular endothelial growth factor (VEGF) in follicular fluid and in granulosa cell cultures in relation to the degree of apoptosis in granulosa cells from patients ...
The glycan structure in recombinant human FSH affects endocrine activity and global gene expression in human granulosa cells
(Elsevier, 2013-12-05)
The aim of this study was to analyse the biological response to different recombinant human FSH (rhFSH)glycosylation variants on the endocrine activity and gene expression at whole-genome scale in human granulosa-like ...
Effect of peritoneal fluid from patients with minimal/mild endometriosis on progesterone release by human granulosa-lutein cells obtained from infertile patients without endometriosis: A pilot study
(ELSEVIER IRELAND LTD, 2008)
Objective: To evaluate the effect of peritoneal fluid (PF) from women without and with minimal/mild endometriosis on progesterone (P) release by cultured human granulosa-lutein cells obtained from infertile patients without ...
Catecholamine uptake, storage, and regulated release by ovarian granulosa cells
(ENDOCRINE SOC, 2008-10)
Catecholamines present in the mammalian ovary are involved in many normal aspects of ovarian functions, including initial follicle growth, steroidogenesis, and pathological states such as polycystic ovary syndrome. Sympathetic ...
Marcadores de apoptose em células da granulosa humanas e sua correlação com parametros clínicos de pacientes submetidas a hiperestimulação ovariana controlada
(Universidade Federal de Minas GeraisBrasilICB - DEPARTAMENTO DE PATOLOGIAPrograma de Pós-Graduação em PatologiaUFMG, 2019-02-21)
The quality of oocytes depends on interactions with surrounding granulosa cells. Granulosa cells are essential in normal follicular maturation process since they produce steroidal hormones and growth factors, and they play ...
Tumor necrosis factor-α activates nuclear factor-κB but does not regulate progesterone production in cultured human granulosa luteal cells
(2007)
Background. The role of tumor necrosis factor-α (TNF-α) in granulosa luteal cell function and steroidogenesis is still controversial. Our aim was to examine the steroidogenic response, together with the simultaneous ...