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The functional links between prion protein and copper
(Sociedad de Biología de Chile, 2006)
Syndecan-1 regulates BMP signaling and dorso-ventral patterning of the ectoderm during early Xenopus development
(ACADEMIC PRESS INC ELSEVIER SCIENCE, 2009)
Extracellular regulation of growth factor signaling is a key event for embryonic patterning. Heparan sulfate proteoglycans (HSPG) are among the molecules that regulate this signaling during embryonic development. Here we ...
Quantitative evaluation of experimental choroidal neovascularization by confocal scanning laser ophthalmoscopy: fluorescein angiogram parallels heparan sulfate proteoglycan expression
(Associação Brasileira de Divulgação Científica, 2010-07-01)
The objective of the present study was to develop a quantitative method to evaluate laser-induced choroidal neovascularization (CNV) in a rat model using Heidelberg Retina Angiograph 2 (HRA2) imaging. The expression of two ...
Internalization and degradation of heparin is not required for stimulus of heparan sulfate proteoglycan synthesis
(Wiley-Blackwell, 2008-11-01)
In vitro, heparin and antithrombotic drugs specifically stimulate the synthesis of an antithrombotic heparan sulfate proteoglycan (HSPG) produced by endothelial cells. the putative heparin binding site(s) that may be related ...
Glial cells modulate heparan sulfate proteoglycan (HSPG) expression by neuronal precursors during early postnatal cerebellar development
(Elsevier B.V., 2010-11-01)
Cerebellum controls motor coordination, balance, eye movement, and has been implicated in memory and addiction. As in other parts of the CNS, correct embryonic and postnatal development of the cerebellum is crucial for ...
Heparan sulfate proteoglycan triggers focal adhesion kinase signaling during Trypanosoma cruzi invasion
(Fundação Oswaldo Cruz. Instituto Oswaldo Cruz., 2021)
In vivo and in vitro cytotoxicity of brown spider venom for blood vessel endothelial cells
(Elsevier B.V., 2001-05-01)
The effect of brown spider (Loxosceles intermedia) venom on endothelial cells was investigated in vivo and in vitro. Morphological and ultrastructural observations by light microscopy and transmission electron microscopy ...
Función de sindecán-4 y fibronectina en la regulación de la vía WNT/β- catenina.
(2013)
La señalización Wnt posee múltiples funciones biológicas, tanto durante el desarrollo embrionario como en la homeostasis adulta. Esta vía de señalización se compone de dos ramas, una denominada "vía Wnt/β-catenina" (o vía ...
Involvement of heparan sulfate proteoglycans in cellular uptake of high molecular weight kininogen
(Walter de Gruyter & Co, 2009-02-01)
In this study, we analyzed the influence of proteoglycans on the interaction between human high molecular weight kininogen (HK) and the cell surface. We found that D5-related peptide inhibits HK-biotin cellular uptake. ...