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Diversity of the KIR gene cluster in an urban Brazilian population
(SPRINGERNEW YORK, 2012)
The activity of natural killer cells depends on the balance between activating and inhibitory signals coming from their receptors. Among these are the killer cell immunoglobulin-like receptors (KIR) that recognize specific ...
The Intergenic Recombinant HLA-B∗46:01 Has a Distinctive Peptidome that Includes KIR2DL3 Ligands
(Elsevier Science, 2017-05)
HLA-B∗46:01 was formed by an intergenic mini-conversion, between HLA-B∗15:01 and HLA-C∗01:02, in Southeast Asia during the last 50,000 years, and it has since become the most common HLA-B allele in the region. A functional ...
Toxoplasma gondii peptide ligands open the gate of the HLA class I binding groove
(eLife Sciences Publications, 2016-01)
HLA class I presentation of pathogen-derived peptide ligands is essential for CD8+ T-cell recognition of Toxoplasma gondii infected cells. Currently, little data exist pertaining to peptides that are presented after T. ...
KIR genes and their human leukocyte antigen ligands in the progression to cirrhosis in patients with chronic hepatitis C
(Elsevier B.V., 2011-11-01)
Natural killer (NK) cells play pivotal roles in immune responses against infection with viruses, such as hepatitis C virus (HCV), and killer cell immunoglobulin-like receptors (KIRs) are related to the activation and ...
KIR genes and their human leukocyte antigen ligands in the progression to cirrhosis in patients with chronic hepatitis C
(Elsevier B.V., 2011-11-01)
Natural killer (NK) cells play pivotal roles in immune responses against infection with viruses, such as hepatitis C virus (HCV), and killer cell immunoglobulin-like receptors (KIRs) are related to the activation and ...
Influência de polimorfismos de genes KIR e de seus ligantes HLA na susceptibilidade ao dengueInfluence of KIR gene polymorphisms and their HLA ligands on susceptibility to dengue
(Universidade Estadual de MaringáBrasilDepartamento de Análises Clínicas e BiomedicinaPrograma de Pós-Graduação em Biociências e FisiopatologiaUEMMaringá, PRCentro de Ciências da Saúde, 2018)