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Hairpin Ribozyme Genes Curtail Alcohol Drinking: from Rational Design to in vivo Effects in the Rat
(Nature Publishing Group, 2016)
Ribozyme genes were designed to reduce voluntary alcohol drinking in a rat model of alcohol dependence. Acetaldehyde generated from alcohol in the liver is metabolized by the mitochondrial aldehyde dehydrogenase (ALDH2) ...
Uncontrolled Citrus psorosis virus infection in Citrus sinensis transgenic plants expressing a viral 24K-derived hairpin that does not trigger RNA silencing
(Academic Press Ltd - Elsevier Science Ltd, 2016-04)
Citrus psorosis virus (CPsV) is the causal agent of psorosis disease of citrus. Pineapple sweet orange plants were transformed with a hairpin construct derived from the viral 24k gene (lines ihp24K). Contrary to expectations, ...
Citrus psorosis virus coat protein-derived hairpin construct confers stable transgenic resistance in citrus against psorosis A and B syndromes
(Springer, 2017-04)
Citrus psorosis virus (CPsV) is the causal agent of psorosis, a serious and widespread citrus disease. Two syndromes of psorosis, PsA and PsB, have been described. PsB is the most aggressive and rampant form. Previously, ...
Flow-induced beta-hairpin folding of the glycoprotein ib alpha beta-switch
(CELL PRESS, 2010)
Desenho e Validação de Primers In Silico para Detecção do Vírus Sincicial Respiratório HumanoDesign and Validation of Primers In Silico for Detection of Human Respiratory Syncytial Virus
(Revista Faculdades Integradas Aparício Carvalho - FIMCA, 2019)
Design of a compact diplexer for multisystem das solutions
(IEEE Computer Society, 2011)
This paper presents a microstrip diplexer for multisystem Distributed Antenna System (DAS) solutions, namely for DCS and UMTS systems. A low-pass quasi-elliptic filter with a stub-like structure is used for the 1800 MHz ...
Control of turbulent transport in supercritical currents by three families of hairpin vortices
(American Physical Society, 2021-06)
We elucidate the turbulent structure of supercritical gravity currents by means of highly resolved simulations that employ up to a billion grid points. Three families of hairpin vortices dominate the near-bed and interface ...