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The distribution and risk effect of GBA variants in a large cohort of PD patients from Colombia and Peru
(Elsevier, 2019)
Background: Mutations in the glucocerebrosidase (GBA) gene are an important risk factor for Parkinson's disease (PD). However, most GBA genetic studies in PD have been performed in patients of European origin and very few ...
Osteocyte Alterations Induce Osteoclastogenesis in an In Vitro Model of Gaucher Disease
(Molecular Diversity Preservation International, 2017-01)
Gaucher disease (GD) is caused by mutations in the glucosylceramidase β (GBA 1) gene that confer a deficient level of activity of glucocerebrosidase (GCase). This deficiency leads to the accumulation of the glycolipid ...
Osteocyte alterations induce osteoclastogenesis in an in vitro model of gaucher disease
(MDPI AG, 2017-01)
Gaucher disease (GD) is caused by mutations in the glucosylceramidase β (GBA 1) gene that confer a deficient level of activity of glucocerebrosidase (GCase). This deficiency leads to the accumulation of the glycolipid ...
Enseñanza y aprendizaje de conceptos asociados a la cinética enzimática en el contexto de la bioquímica de alimentos.
(Universidad Pedagógica NacionalLicenciatura en QuímicaFacultad de Ciencia y Tecnología, 2022)
Este trabajo de grado se propone el diseño de una unidad didáctica enmarcada en el modelo Aprendizaje Basado en Problemas (ABP) para la enseñanza de conceptos asociados a la cinética enzimática. En donde se plantea tres ...