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The methylation patterns of the IGF2 and IGF2R genes in bovine spermatozoa are not affected by flow-cytometric sex sorting.

CARVALHO, J. O.; MICHALCZECHEN-LACERDA, V. A.; SARTORI, R.; RODRIGUES, F. C.; BRAVIM, O.; FRANCO, M. M.; DODE, M. A. N. (2012)

Impact of hypoxia on IGF-I, IGF-II, IGFBP-3, ALS and IGFBP-1 regulation and on IGF1R gene expression in children

Custodio, Rodrigo Jose; do Carmo Custodio, Viviane Imaculada; Scrideli, Carlos Alberto; Sader Milani, Soraya Lopes; Cervi, Maria Celia; Cupo, Palmira; Martinelli, Carlos Eduardo, Jr. (CHURCHILL LIVINGSTONEEDINBURGH, 2012)

Hypoxia is one of many factors involved in the regulation of the IGF system. However, no information is available regarding the regulation of the IGF system by acute hypoxia in humans. Objective: The aim of this study was ...

Igf2 And Igf1r In Pediatric Adrenocortical Tumors: Roles In Metastasis And Steroidogenesis

Lira; RCP; Fedatto; PF; Antonio; DSM; Leal; LF; Martinelli; CE; de Castro; M; Tucci; S; Neder; L; Ramalho; L; Seidinger; AL; Cardinalli; I; Mastellaro; MJ; Yunes; JA; Brandalise; SR; Tone; LG; Antonini; SRR; Scrideli; CA (BIOSCIENTIFICA LTDBRISTOL, 2016)

Partial IGF-1 deficiency is sufficient to reduce heart contractibility, angiotensin II sensibility, and alter gene expression of structural and functional cardiac proteins

Gabriel Amador Aguirre; Irene Martín Del Estal; María Inmaculada Castilla de Cortázar Larrea; José Luis González Guerra

Genetic disorders of GH action pathway

Domene, Horacio Mario; Fierro Carrión, Gustavo (Churchill Livingstone, 2018-02)

While insensitivity to GH (GHI) is characterized by low IGF-I levels, normal or elevated GH levels, and lack of IGF-I response to GH treatment, IGF-I resistance is characterized by elevated IGF-I levels with normal/high ...

Imprinted gene expression in in vivo- and in vitro-produced bovine embryos and chorio-allantoic membranes

PERECIN, F.; MEO, S. C.; YAMAZAKI, W.; FERREIRA, C. R.; MERIGHE, G. K. F.; MEIRELLES, F. V.; GARCIA, J. M. (FUNPEC-EDITORA, 2009)

Cloning by nuclear transfer is often associated with poor results due to abnormal nuclear reprogramming of somatic donor cells and altered gene expression patterns. We investigated the expression patterns of imprinted genes ...

Molecular and cellular effects of insulin-like growth factor-1 and LongR3-IGF-1 on in vitro maturation of bovine oocytes: comparative study

Universidade Estadual Paulista (Unesp); Universidade de Brasília (UnB); Universidade de São Paulo (USP) (Churchill Livingstone, 2020-12-01)

Addition effects of insulin-like growth factor-1 (IGF-1) and its synthetic analogue insulin-like growth factor-1 recombinant-3 (LongR3-IGF-1) after in vitro maturation (IVM) of cattle cumulus-oocyte complexes (COCs) were ...

Expanding Genetic and Functional Diagnoses of IGF1R Haploinsufficiencies

Ocaranza Osses, Paula; Golekoh, Marjorie C.; Andrew, Shayne F.; Guo, Michael H.; Kaplowitz, Paul; Saal, Howard; Rosenfeld, Ron G.; Dauber, Andrew; Cassorla Goluboff, Fernando; Backeljauw, Philippe F.; Hwa, Vivian (Karger, 2017)

Background: The growth-promoting effects of IGF-I is mediated through the IGF-I receptor (IGF1R), a widely expressed cell-surface tyrosine kinase receptor. IGF1R copy number variants (CNV) can cause pre- and postnatal ...

Genetic structure and population dynamics of autochthonous and modern porcine breeds. Analysis of the IGF2 and MC4R genes that determine carcass characteristicsGenetic structure and population dynamics of autochthonous and modern porcine breeds. Analysis of the IGF2 and MC4R genes that determine carcass characteristics

Llambí, Silvia; Montenegro, María; Gagliardi, Rosa; Burgos, Carmen; Hidalgo, Jorge; López-Buesa, Pascual; Arruga, María V. (Faculty of Veterinary Sciences - Universidad Austral de Chile, 2020)

New insights into IGF-1 signaling in the heart

Troncoso Cotal, Rodrigo Hernán; Ibarra, Cristián; Vicencio, José Miguel; Jaimovich Pérez, Enrique; Lavandero González, Sergio (Elsevier, 2014)

Insulin-like growth factor 1 (IGF-1) signaling regulates contractility, metabolism, hypertrophy, autophagy, senescence, and apoptosis in the heart. IGF-1 deficiency is associated with an increased risk of cardiovascul ...

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