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Novel interactions of GRP78: UPR and estrogen responses in the brain
(Wiley, 2013-06)
Glucose-regulated protein 78 (GRP78; 78 kDa) belongs to a group of highly conserved heat shock proteins (Hsp) with important functions at the cellular level. The emerging interest for GRP78 relies on its different functions, ...
Hyperandrogenism Decreases GRP78 Protein Level and Glucose Uptake in Human Endometrial Stromal Cells
(SAGE, 2016)
Background: Women with polycystic ovary syndrome (PCOS) exhibit a low fertility by chronic hyperandrogenemia. Different evidence have shown that androgens could regulate the endoplasmic reticulum (ER) homeostasis and glucose ...
Interaction of glucokinase with the liver regulatory protein is conferred by leucine-asparagine motifs of the enzyme
(American Diabetes Association, 2005-10)
The glucokinase regulatory protein (GRP) plays a pivotal role in the regulation of metabolic flux in liver by the glucose-phosphorylating enzyme glucokinase. Random peptide phage display library screening for binding ...
Prognostic significance of GRP78 expression patterns in breast cancer patients receiving adjuvant chemotherapy
(Wichtig EditoreMilanItália, 2011)
Low resolution structure and stability studies of human GrpE#2, a mitochondrial nucleotide exchange factor
(Elsevier Science IncNew YorkEUA, 2006)
Glucose regulated protein 78 (GRP78) interacts with Zika virus envelope and is required for a productive infection
Zika virus (ZIKV) is a member of the Flaviviridae family and was until recently a relatively obscure tropical disease. Subsequently, ZIKV has been shown to be the causative agent of fetal abnormalities and Guillain-Barré ...
Glucose-regulated protein 78 (Grp78/BiP) is secreted by human oviduct epithelial cells and the recombinant protein modulates sperm-zona pellucida binding
(Elsevier Science Inc, 2010-03)
To determine the secretion of Grp78 by human oviduct epithelial cells, its association to spermatozoa, and its involvement in gamete interaction. Prospective study. Basic research laboratory. Semen samples obtained from ...
Investigação do efeito proliferativo e migratório do peptídeo liberador de gastrina (GRP) sobre uma linhagem de adenocarcinoma pulmonar
(Pontifícia Universidade Católica do Rio Grande do SulPorto Alegre, 2014)
Lung cancer is the most commonly diagnosed type of cancer and the leading cause of cancer related mortality in the world, causing nearly one million deaths per year. Among all histological types, adenocarcinoma is the most ...