Buscar
Mostrando ítems 1-10 de 97
Long-term sertraline treatment increases expression and decreases phosphorylation of glycogen synthase kinase-3B in platelets of patients with late-life major depression
(PERGAMON-ELSEVIER SCIENCE LTDOXFORD, 2012)
Background: Abnormal regulation of glycogen synthase kinase 3-beta (GSK3B) activity has been implicated in the pathophysiology of mood disorders. Many pharmacological agents, including antidepressants, can modulate GSK3B. ...
Peroxisome proliferator-activated receptor gamma is expressed in hippocampal neurons and its activation prevents beta-amyloid neurodegeneration: role of Wnt signaling
(ELSEVIER INC, 2005)
The molecular pathogenesis of Alzheimer's disease (AD) involves the participation of the amyloid-beta-peptide (Abeta), which plays a critical role in the neurodegeneration that triggers the disease. Peroxisome proliferat ...
Insights into the Interactions between Maleimide Derivates and GSK3 beta Combining Molecular Docking and QSAR
(PUBLIC LIBRARY SCIENCE, 2014)
Downhill Running-based Overtraining Protocol Improves Hepatic Insulin Signaling Pathway Without Concomitant Decrease Of Inflammatory Proteins
(PUBLIC LIBRARY SCIENCESAN FRANCISCO, 2015)
Early requirement of Hyaluronan for tail regeneration in Xenopus tadpoles
(COMPANY OF BIOLOGISTS LTD, 2009)
Tail regeneration in Xenopus tadpoles is a favorable model system to understand the molecular and cellular basis of tissue regeneration. Although turnover of the extracellular matrix (ECM) is a key event during tissue ...
Angiotensin-(1-7) stimulates the phosphorylation of Akt in rat extracardiac tissues in vivo via receptor Mas
(Elsevier Science, 2010-04)
The in vivo effect of angiotensin (ANG)-(1-7) on the activation of insulin signaling transduction in rat extracardiac tissues is unknown. Thus, in the present study, we evaluated the ability of ANG-(1-7) to stimulate the ...