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GDNF and GFRα1 Are Required for Proper Integration of Adult-Born Hippocampal Neurons
(Elsevier Inc, 2019-12)
The glial cell line-derived neurotrophic factor (GDNF) is required for the survival and differentiation of diverse neuronal populations during nervous system development. Despite the high expression of GDNF and its receptor ...
Increased glial-derived neurotrophic factor in the small intestine of rats infected with the tapeworm, Hymenolepis diminuta
(Wiley-Blackwell, 2008-12-01)
The neurotrophin, glial-derived neurotrophic factor (GDNF), is essential for the development of the enteric nervous system (ENS) in both the embryo and neonate and may be important for maintenance and plasticity of ENS. ...
Increased glial-derived neurotrophic factor in the small intestine of rats infected with the tapeworm, Hymenolepis diminuta
(Wiley-Blackwell, 2008-12-01)
The neurotrophin, glial-derived neurotrophic factor (GDNF), is essential for the development of the enteric nervous system (ENS) in both the embryo and neonate and may be important for maintenance and plasticity of ENS. ...
GDNF/GFRα1 Complex Abrogates Self-Renewing Activity of Cortical Neural Precursors Inducing Their Differentiation
(Cell Press, 2018-03)
The balance between factors leading to proliferation and differentiation of cortical neural precursors (CNPs) determines the correct cortical development. In this work, we show that GDNF and its receptor GFRα1 are expressed ...
Fatores neurotróficos na epilepsia de lobo temporal
(Universidade Federal de Minas GeraisBrasilICB - INSTITUTO DE CIÊNCIAS BIOLOGICASPrograma de Pós-Graduação em NeurociênciasUFMG, 2019-02-20)
Background: Epilepsy is one of the most common neurological diseases affecting 0.5 to 2%
of the population worldwide. Temporal lobe epilepsy (TLE) is the most common epileptic
syndrome in adults and is often refractory ...
The GDNF-GFRα1 complex promotes the development of hippocampal dendritic arbors and spines via NCAM
(Company of Biologists, 2016-11)
The formation of synaptic connections during nervous system development requires the precise control of dendrite growth and synapse formation. Although glial cell line-derived neurotrophic factor (GDNF) and its receptor ...
Circulating Glial-derived neurotrophic factor is reduced in late-life depression
(PERGAMON-ELSEVIER SCIENCE LTDOXFORD, 2012)
Background: The Glial Cell-line derived neurotrophic factor (GDNF) is part of the TGF-beta superfamily and is abundantly expressed in the central nervous system. Changes in GDNF homeostasis have been reported in affective ...
Effect of GDNF on neuroblast proliferation and photoreceptor survival: additive protection with docosahexaenoic acid
(Association for Research in Vision and Ophthalmology, 2001-11)
Purpose. In a previous study, it was reported that docosahexaenoic acid (DHA) is essential to postpone apoptosis and to promote differentiation of rat retina photoreceptors in vitro. In the current study, the protective ...