Buscar
Mostrando ítems 1-10 de 78
Regulation of Pleiotrophin and Fyn in the striatum of rats undergoing L-DOPA-induced dyskinesia
(Elsevier Ireland, 2018-02)
L-DOPA is the gold standard pharmacological therapy for symptomatic treatment of Parkinson´s disease (PD), however, its long-term use is associated with the emergence of L-DOPA-induced dyskinesia (LID). Understanding the ...
cAMP-Fyn signaling in the dorsomedial striatum direct pathway drives excessive alcohol use
(Nature Publishing Group, 2020-05)
Fyn kinase in the dorsomedial striatum (DMS) of rodents plays a central role in mechanisms underlying excessive alcohol intake. The DMS is comprised of medium spiny neurons (MSNs) that project directly (dMSNs) or indirectly ...
Fyn knock-down prevents levodopa-induced dyskinesia in a mouse model of parkinson’s disease
(Society for Neuroscience, 2021-07)
Dopamine replacement by levodopa (L-DOPA) is the most widely used therapy for Parkinson’s disease (PD), however patients often develop side effects, known as L-DOPA-induced dyskinesia (LID), that usually need therapeutic ...
Fyn Mediates Leptin Actions in the Thymus of Rodents
(Public Library ScienceSan FranciscoEUA, 2009)
The Kinase Fyn As a Novel Intermediate in l-DOPA-Induced Dyskinesia in Parkinson’s Disease
(Humana Press, 2017-08)
Dopamine replacement therapy with l-DOPA is the treatment of choice for Parkinson’s disease; however, its long-term use is frequently associated with l-DOPA-induced dyskinesia (LID). Many molecules have been implicated in ...
Oligodendrocyte differentiation and signaling after transferrin internalization: a mechanism of action
(Elsevier, 2013-10)
Oligodendrocytes are the cells producing the myelin membrane around the axons in the central nervous system and, although apotransferrin (aTf) is required for oligodendrocyte differentiation, the underlying mechanisms are ...