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Rol de esfingosina-1-fosfato en la progresión del melanoma inducida por NF-κB
(2017-01-01)
Considering that: a) deregulation of NF-κB signaling pathway is a common feature of many cancer types and modulates inflammation, invasion and angiogenesis, among other tumor characteristics, and b) sphingosine-1-phosphate ...
Structural interaction and functional regulation of polycystin-2 by filamin
(Public Library of Science, 2012-07)
Filamins are important actin cross-linking proteins implicated in scaffolding, membrane stabilization and signal transduction, through interaction with ion channels, receptors and signaling proteins. Here we report the ...