Buscar
Mostrando ítems 1-10 de 77
A fatty acid synthase gene (FASN3) from the integument tissue of Rhodnius prolixus contributes to cuticle water loss regulation
(Wiley Blackwell Publishing, Inc, 2019-12)
Fatty acid synthase is a multifunctional enzyme involved in the formation of fatty acids. Despite the role of fatty acids in cell signalling and energy metabolism, and as precursors to pheromones and hydrocarbons that ...
Associations of FASN gene polymorphisms with economical traits in Nellore cattle (Bos primigenius indicus)
(Springer, 2012-12-01)
The aim of this study was to identify molecular markers to be applied to marker-assisted selection. Three SNPs of the FASN gene were studied. PCR-RFLP was used for genotyping. The SNPs g.17924A > G, g.17860C > T and g.15603A ...
Associations of FASN gene polymorphisms with economical traits in Nellore cattle (Bos primigenius indicus)
(Springer, 2012-12-01)
The aim of this study was to identify molecular markers to be applied to marker-assisted selection. Three SNPs of the FASN gene were studied. PCR-RFLP was used for genotyping. The SNPs g.17924A > G, g.17860C > T and g.15603A ...
A non-synonymous single nucleotide polymorphism in FASN gene alters FASN enzyme activity in subcutaneous and intramuscular adipose tissue in Holstein Friesian steers
(Chile. Universidad Mayor, 2020)
The FASN enzyme plays a key role in fatty acids synthesis as the main long-chain fatty acid synthesizer. A non-synonymous SNP (single nucleotide polymorphism) (g.17925A>G) located in the thiocsterase domain of this enzyme ...
The metastasis inducer CCN1 (CYR61) activates the fatty acid synthase (FASN)-driven lipogenic phenotype in breast cancer cells
(Impact journals, 2016-07-22)
The angiogenic inducer CCN1 (Cysteine-rich 61, CYR61) is differentially activated in metastatic breast carcinomas. However, little is known about the precise mechanisms that underlie the pro-metastatic actions of CCN1. ...
Análisis de polimorfismo de nucleótido simple en el gen FASN y su relación con características de producción en pollos
(Instituto Nacional de Tecnología Agropecuaria, 2013-04)
El objetivo de este trabajo es evaluar la posible asociación entre un polimorfismo de nucleótido simple (SNP) del gen FASN y cada uno de los siguientes caracteres productivos: Consumo de Alimento (CA), Ganancia de Peso ...
Clinical and therapeutic relevance of the metabolic oncogene fatty acid synthase in HER2+ breast cancer
(Universidad de Murcia, 2017-07)
Fatty acid synthase (FASN) is a key lipogenic enzyme for de novo fatty acid biosynthesis and a druggable metabolic oncoprotein that is activated in most human cancers. We evaluated whether the HER2-driven lipogenic phenotype ...
Fatty acid synthase is a key enabler for endocrine resistance in heregulin-overexpressing luminal b-like breast cancer
(MDPI AG, 2020-10)
HER2 transactivation by the HER3 ligand heregulin (HRG) promotes an endocrine-resistant phenotype in the estrogen receptor-positive (ER+) luminal-B subtype of breast cancer. The underlying biological mechanisms that link ...