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Nkcc1 Inhibition Decrease Altered Excitability Of Dentate Gyrus In Adult Epileptic Conditions
(2014)
Granule cells of the dentate gyrus (GCDG) are the gatekeepers of hippocampal circuit by an intrinsically
low cell excitability, which is pathologically increased in Temporal Lobe Epilepsy. Alterations in balance
between ...
Emergent Orientation Selectivity from Random Networks in Mouse Visual Cortex
(Elsevier, 2018-08)
The connectivity principles underlying the emergence of orientation selectivity in primary visual cortex (V1) of mammals lacking an orientation map (such as rodents and lagomorphs) are poorly understood. We present a ...
Differential Coupling of Adult-Born Granule Cells to Parvalbumin and Somatostatin Interneurons
(Elsevier Inc, 2020-01)
A strong GABAergic tone imposes sparse levels of activity in the dentate gyrus of the hippocampus. This balance is challenged by the addition of new granule cells (GCs) with high excitability. How developing GCs integrate ...
Role of the Chloride co-transporter NKCC1 in excitability of dentate Gyrus in chorinic epilepsy
(2013)
Granule cells of the dentate gyrus (GCDG) are the
gatekeepers of the tri-synaptic hippocamapal
circuit in part by an intrinsically low cell excitability,
which is pathologically increased in Temporal Lobe
Epilepsy. ...
Chloride transporte NKCC1 involvment in reduced excitability in an animal model of schizophrenia
(2013)
Schizophrenia is one of the most common
neurological diseases in human population,
however there is no common hypothesis to
explaining all its features. This is due in part to a
inability of animal models to reproduce ...
Dynamics of cortical computations underlying attentive states
(2021)
Spontaneous fluctuations occur at different spatial and temporal scales in the brain. Depending on its scale, these activities can show characteristic hallmarks. From a mesoscale perspective, in spontaneous conditions, ...
Complexity and 1/f slope jointly reflect brain states
(Nature Research, 2023)
Characterization of brain states is essential for understanding its functioning in the absence of external stimuli. Brain states differ on their balance between excitation and inhibition, and on the diversity of their ...
Structural and functional abnormalities in the olfactory system of fragile x syndrome models
(Frontiers Media S.A., 2019)