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Components of variation of polygenic systems with digenic epistasis
(Genetics and Molecular Biology, 2019)
Dominance, epistasis, heritabilities and expected genetic gains
(Genetics and Molecular Biology, 2019)
Phantom epistasis in genomic selection: on the predictive ability of epistatic models
(Genetics Society of America, 2020-09-01)
Genomic selection uses whole-genome marker models to predict phenotypes or genetic values for complex traits. Some of these models fit interaction terms between markers, and are therefore called epistatic. The biological ...
Bayesian reversible-jump for epistasis analysis in genomic studies
(BioMed Central, 2016)
Abstract
Background
The large amount of data used in genomic analysis has allowed geneticists to achieve some understanding of the genetic architecture of complex traits. ...
Multiethnic GWAS Reveals Polygenic Architecture of Earlobe Attachment
(Elsevier, 2017)
The genetic basis of earlobe attachment has been a matter of debate since the early 20th century, such that geneticists argue both for and against polygenic inheritance. Recent genetic studies have identified a few loci ...
Interaction among nitric oxide (NO)-related genes in migraine susceptibility
(SpringerDordrecht, 2012)
Epistasis among eNOS, MMP-9 and VEGF maternal genotypes in hypertensive disorders of pregnancy
(NATURE PUBLISHING GROUPLONDON, 2012)
Polymorphisms of the endothelial nitric oxide synthase (eNOS), matrix metalloproteinase-9 (MMP-9) and vascular endothelial growth factor (VEGF) genes were shown to be associated with hypertensive disorders of pregnancy. ...
Gene Families, Epistasis and the Amino Acid Preferences of Protein Homologs
(SAGE PUBLICATIONS LTD, 2019)
In order to preserve structure and function, proteins tend to preferentially conserve amino acids at particular sites along the sequence. Because mutations can affect structure and function, the question arises whether the ...