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Evaluation of imazethapyr-induced DNA oxidative damage by alkaline Endo III- and Fpg-modified single-cell gel electrophoresis assay in Hypsiboas pulchellus tadpoles (Anura, Hylidae)
(Academic Press Inc Elsevier Science, 2017-08)
Imazethapyr (IMZT) is a selective postemergent herbicide with residual action. Available data analyzing its effects in aquatic vertebrates are scarce. In previous studies, we demonstrated that IMZT induces lesions into the ...
Antioxidant, phase II and III responses induced by lipoic acid in the fish Jenynsia multidentata (Anablapidae) and its influence on endolsulfan accumulation and toxicity
(Elsevier, 2013-11-01)
Antioxidants like lipoic acid (LA) are known to trigger augmented antioxidant and phase II and III responses. This study aimed to evaluate the effect of LA in P-glycoprotein (Pgp) expression, glutathione-S-transferase (GST) activity, total antioxidant competence, levels of lipid peroxides (TBARS) and accumulation of the organochlorine insecticide endosulfan (Endo: α-, β-isomers and sulfate metabolite) in different organs of the fish Jenynsia multidentata. One hundred and twenty females (1.55 ± 0.07 g) were fed during 8 days with (n = 60) or without (n = 60) a LA enriched ration (6000 mg/kg). Four experimental groups were defined: −LA/−Endo; +LA/−Endo; −LA/+Endo; and +LA/+Endo. Endo groups were exposed during 24 h to 1.4 μg of insecticide/L. Results showed that only LA induced a significant increment in liver Pgp expression. GST activity was augmented in liver after exposure to LA or Endo. TBARS levels were lowered in liver and gills after LA pre-treatment. Total antioxidant capacity was lowered in liver of Endo exposed fish, a result that was reversed by LA pre-treatment. It is concluded that LA induced the expected effects in terms of Pgp expression, GST activity and reduced TBARS levels although favored α-Endo accumulation in brain. However, the Endo metabolism to the more persistent endosulfan sulfate was not facilitated by LA pre-treatment....
Avaliação da capacidade de remoção da camada residual dentinária com o uso do Endo PTC em diferentes formulações, associado a duas concentrações de hipoclorito de sódio, utilizando ou não irrigação final com EDTA
(Programa de Pós- Graduação em Odontologia da UFBA, 2010)
A ação dos instrumentos nas paredes do canal radicular proporciona a formação da camada residual, que é um extrato de matéria orgânica e inorgânica, de aparência amorfa, superfície irregular e granulosa que é depositada ...
III Simpósio de Engenharia de Alimentos: interdisciplinaridade e inovação na engenharia de alimentos
(Universidade Federal de Minas GeraisBrasilICA - INSTITUTO DE CIÊNCIAS AGRÁRIASUFMGICA - UFMG, 2019-08)
Genotoxicity of the herbicide imazethapyr in mammalian cells by oxidative DNA damage evaluation using the Endo III and FPG alkaline comet assays
(Springer Heidelberg, 2017-04)
We evaluated the role of oxidative stress in the genotoxic damage induced by imazethapyr (IMZT) and its formulation Pivot® in mammalian CHO-K1 cell line. Using the alkaline comet assay, we observed that a concentration of ...
Auxinic herbicides induce oxidative stress on Cnesterodon decemmaculatus (Pisces: Poeciliidae)
(Springer Heidelberg, 2019-07)
Pesticides might increase the production of reactive oxygen species (ROS). Dicamba (DIC) and 2,4-dichlorophenoxyacetic acid (2,4-D) are auxinic herbicides commonly applied in agroecosystems to control unwanted weeds. We ...
Eucalyptol, Orange Oil, and Xilodent Solubility on Three Endodontic Sealants: An in vitro Study
(Jaypee Journals. International Journal of Experimental Dental SciencePE, 2018)
Aim: To compare the in vitro solubility of eucalyptol, orange oil, and xilodent on three endodontic sealers based on their commercial brand and immersion time.
Materials and methods: A total of 240 samples of endodontic ...