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Dysregulation of stromal derived factor 1/CXCR4 axis in the megakaryocytic lineage in essential thrombocythemia

Salim, Juan Pablo; Goette, Nora Paula; Lev, Paola Roxana; Chazarreta, Carlos Daniel; Heller, Paula Graciela; Alvarez, Clarisa Ester; Molinas, Felisa Concepción; Marta, Rosana Fernanda (Wiley Blackwell Publishing, Inc, 2009-01)

This study investigated the involvement of chemokines including stromal derived factor 1 (SDF-1), interleukin 8 (IL-8), growth-related oncogene alpha (GRO-a) and their receptors, CXCR4, CXCR2 and CXCR1 in essential ...

Cytogenetics, JAK2 and MPL mutations in polycythemia vera, primary myelofibrosis and essential thrombocythemia

Santos, Leonardo Caires dos; Ribeiro, Juliana Corrêa da Costa; Silva, Neusa Pereira da; Cerutti, Janete Maria; Silva, Maria Regina Regis da; Chauffaille, Maria de Lourdes Lopes Ferrari (Associação Brasileira de Hematologia e Hemoterapia e Terapia Celular, 2011-12-01)

BACKGROUND: The detection of molecular and cytogenetic alterations is important for the diagnosis, prognosis and classification of myeloproliferative neoplasms. OBJECTIVE: The aim of this study was to detect the following ...

Fatal Ischemic Stroke Following Tityus Serrulatus Scorpion Sting In A Patient With Essential Thrombocythemia

Bucaretchi; Fabio; De Capitani; Eduardo M.; Fernandes; Carla B.; Santos; Thiago M.; Zamilute; Igor A. G.; Hyslop; Stephen (Taylor & Francis LtdAbingdon, 2016)

JAK2 V617F prevalence in Brazilian patients with polycythemia vera, idiopathic myelofibrosis and essential thrombocythemia

Monte-Mór, Bárbara da Costa Reis; Cunha, Anderson Ferreira da; Pagnano, Kátia Bórgia Barbosa; Saad, Sara Terezinha; Lorand-Metze, Irene; Costa, Fernando Ferreira (Sociedade Brasileira de Genética, 2007)

Concomitant Essential Thrombocythemia With Jak2 V617f Mutation In A Patient With Chronic Myeloid Leukemia With Major Molecular Response With Imatinib And Long-term Follow-up

Barbosa Pagnano; Katia Borgia; Delamain; Marcia Torresan; Magnus; Mariana Munari; Vassallo; Jose; De Souza; Carmino Antonio; De Almeida; Daiane; Lorand-Metze; Irene (Spandidos Publ LtdAthens, 2016)

MPL immunohistochemical expression as a novel marker for essential thrombocythemia and primary myelofibrosis differential diagnosis

Ponce, Cesar Cilento [UNIFESP]; Chauffaille, Maria de Lourdes F. [UNIFESP]; Ihara, Silvia Saiuli M. [UNIFESP]; Silva, Maria Regina R. [UNIFESP] (Elsevier B.V., 2012-01-01)

To evaluate the grading of fibrosis and immunohistochemical expression of MPL in bone marrow biopsies of ET and PMF. Fibrosis in bone marrow biopsies (BMBs) was evaluated according to the European Consensus for grading of ...

Clinical features of JAK2V617F- or CALRmutated essential thrombocythemia and primary myelofibrosis

Monte-Mor, Bárbara da Costa Reis; Zalcberg, Ilana; Correia, William Dias; Coelho, Ana Caroline; Silva, Jackline de Paula Ayres; Solza, Cristiana; Daumas, Adelmo Henrique; Bonamino, Martin Hernán; Santos, Fábio Pires de Souza; Datoguia, Tarcila Santos; Pereira, Welbert de Oliveira; Lisboa, Bianca Cristina Garcia; Hamerschlak, Nelson; Campregher, Paulo Vidal; Ramos, Clarisa Fernandes; Machado Neto, João Agostinho; Pagnano, Katia Borgia Barbosa; Traina, Fabíola (Elsevier, 2016)

Abnormal regulation of soluble and anchored IL-6 receptor in monocytes from patients with essential thrombocythemia

Goette, Nora Paula; Lev, Paola Roxana; Heller, Paula Graciela; Glembotsky, Ana Claudia; Chazarreta, Carlos Daniel; Salim, Juan Pablo; Molinas, Felisa Concepcion; Marta, Rosana Fernanda (Elsevier Inc, 2010-10)

Objective: In a previous study, we found increased plasma soluble receptor for interleukin-6 (sIL-6R) levels in patients with essential thrombocythemia (ET) that could promote megakaryopoiesis through IL-6 binding and ...

Platelet toll-like receptors mediate thromboinflammatory responses in patients with essential thrombocythemia

Marin Oyarzún, Cecilia Paola; Glembotsky, Ana Claudia; Goette, Nora Paula; Lev, Paola Roxana; de Luca, Geraldine; Baroni Pietto, Maria Constanza; Moiraghi, Beatriz; Castro Ríos, Miguel A.; Vicente, Angeles; Marta, Rosana Fernanda; Schattner, Mirta Ana; Heller, Paula Graciela (Frontiers Research Foundation, 2020-04)

Essential thrombocythemia (ET) is comprised among chronic myeloproliferative neoplasms (MPN) and is caused by driver mutations in JAK2, CALR and MPL, which lead to megakaryocyte proliferation and prominent thrombocytosis. ...

Apoptosis- and cell cycle-related genes methylation profile in myeloproliferative neoplasms

Tognon, Raquel; Nunes, Natalia S.; Ambrosio, Luciana; Souto, Elizabeth Xisto; Perobelli, Leila; Simoes, Belinda Pinto; Lima Souza, Mariana Cristina [UNIFESP]; Chauffaille, Maria de Lourdes [UNIFESP]; de Castro, Fabiola Attie (Taylor & francis ltd, 2016)

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