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Immunomodulatory effect of cathelicidins in response to a beta-glucan in intestinal epithelial cells from rainbow trout
(Elsevier, 2015)
The aim of the present study was to characterize intestinal immune mechanisms involved in the response to beta-glucans in rainbow trout. Among the immune effectors regulated in response to immunostimulants, host defense ...
Neonatal endotoxin stimulation is associated with a long-term bronchiolar epithelial expression of innate immune and anti-allergic markers that attenuates the allergic response
(Public Library of Science, 2020-05)
Allergic asthma is the most common phenotype of the pathology, having an early-onset in childhood and producing a Th2-driven airways remodeling process that leads to symptoms and pathophysiological changes. The avoidance ...
Androgen regulation of host defenses and response to inflammatory stimuli in the prostate gland
(Academic Press Ltd - Elsevier Science Ltd, 2017-11)
The prostate gland is a strictly androgen-dependent organ which is also the main target of infectious and inflammatory diseases in the male reproductive tract. Host defenses and immunity of the gland have unique features ...
Respiratory epithelial cells: more than just a physical barrier to fungal infections
(MDPI, 2022-05-24)
The respiratory epithelium is highly complex, and its composition varies along the conducting airways and alveoli. In addition to their primary function in maintaining the respiratory barrier and lung homeostasis for gas ...
Transient receptor potential channel 1 deficiency impairs host defense and proinflammatory responses to bacterial infection by regulating protein kinase Cα signaling
(American Society for Microbiology, 2015-08)
Transient receptor potential channel 1 (TRPC1) is a nonselective cation channel that is required for Ca2+ homeostasis necessary for cellular functions. However, whether TRPC1 is involved in infectious disease remains ...
Immunobiotics for the bovine host: their interaction with intestinal epithelial cells and their effect on antiviral immunity
(Frontiers Research Foundation, 2018-03)
The scientific community has reported several cases of microbes that exhibit elevated rates of antibiotic resistance in different regions of the planet. Due to this emergence of antimicrobial resistant microorganisms, the ...
Paneth cells and their multiple functions
(2022-01-01)
The small intestine mucosa is lined by specialized cells that form the crypt-villus axis, which expands its surface. Among the six intestinal epithelial cell types, the Paneth cell is located at the base of the crypt, and ...
Immunological features protect against candida spp.
(2015-01-01)
The epithelial mucosa is an important component of the host immune defense and immune surveillance since it is the first layer that most microorganisms initially contact. The most important function of the immune system ...