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Pharmacokinetic Parameters of HIV-1 Protease Inhibitors
(2020-06-17)
Since the beginning of the HIV epidemic, research has been carried out to control the virus. Understanding the mechanisms of replication has given access to the various classes of drugs that over time have transformed AIDS ...
Detección de resistencia primaria en pacientes chilenos infectados por VIH
(Sociedad Médica de Santiago, 2007)
Advances in the development of entry inhibitors for sialic-acid-targeting viruses
Over the past decades, several antiviral drugs have been developed to treat a range
of infections. Yet the number of treatable viral infections is still limited, and resistance
to current drug regimens is an ever-growing ...
Antiviral Resistance and Correlates of Virologic Failure in the first Cohort of HIV-Infected Children Gaining Access to Structured Antiretroviral Therapy in Lima, Peru: A Cross-Sectional Analysis
(BioMed Central, 2013)
Background: The impact of extended use of ART in developing countries has been enormous. A thorough understanding of all factors contributing to the success of antiretroviral therapy is required. The current study aims to ...
HIV-1 drug resistance genotypic profiles in children with undetectable plasma viremia during antiretroviral therapy
(Brazilian Society of Infectious Diseases, 2011)
Treatment of HIV-1 infection with highly active antiretroviral therapy has led to sustained viral suppression in the plasma in a large number of children. However, studies have suggested that the integrated provirus in ...
HIV-1 drug resistance genotypic profiles in children with undetectable plasma viremia during antiretroviral therapy
(Brazilian Society of Infectious Diseases, 2011-02-01)
Treatment of HIV-1 infection with highly active antiretroviral therapy has led to sustained viral suppression in the plasma in a large number of children. However, studies have suggested that the integrated provirus in ...
Pesquisas brasileiras biomédicas e epidemiológicas face às metas da UNGASSBrazilian biomedical and epidemiological research vis-à-visthe UNGASS targets
(Faculdade de Saúde Pública da Universidade de São Paulo, 2010)
Evaluation of viral resistance to Reverse Transcriptase Inhibitors (RTI) in HIV-1-infected patients before and after 6 months of single or double antiretroviral therapy
(The Brazilian Journal of Infectious Diseases and Contexto Publishing, 2001-08)
We evaluated samples of peripheral blood mononuclear (PBMC) cells from 46 AIDS patients, before starting therapy with HIV-1 reverse transcriptase inhibitors (RTI), and after 6 months of drug use. PBMC were stored and tested ...
Búsqueda de mutaciones en el gen UL 97 asociadas a resistencia a ganciclovir en citomegalovirus obtenidos desde muestras biológicas de pacientes chilenos
(2010)
Background: Long term use of ganciclovir (GCV) is associated with acquired resistance to it. Ninety percent of the responsible mutations occur in cytomegalovirus (CMV) UL97 gene. Aim: To search for these mutations, comparing ...