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Apical contacts stemming from incomplete delamination guide progenitor cell allocation through a dragging mechanism
(Elife Sciences Publications, 2021)
The developmental strategies used by progenitor cells to allow a safe journey from their induction place towards the site of terminal differentiation are still poorly understood. Here, we uncovered a mechanism of progenitor ...
Origin and shaping of the laterality organ in zebrafish
(The Company of Biologists, 2008-07)
Handedness of the vertebrate body plan critically depends on transient embryonic structures/organs that generate cilia-dependent
leftward fluid flow within constrained extracellular environments. Although the function of ...
Planar cell polarity signalling regulates cell adhesion properties in progenitors of the zebrafish laterality organ
(Company of Biologists Ltd, 2010)
Organ formation requires the precise assembly of progenitor cells into a functional multicellular structure. Mechanical forces probably participate in this process but how they influence organ morphogenesis is still unclear. ...
Role of the Planar Cell Polarity Pathway in the Morphogenesis of the Laterality Organ in Zebrafish
(Universidad de Chile, 2009)
A pesar de su aparente simetría bilateral, el plan corporal de los vertebrados presenta consitentes asimetrías en localización, estructura y función de diversos órganos internos como el corazón, los intestinos y el cerebro. ...