Many prokaryotic nucleoid proteins bend DNA and form extended helical protein-DNA fibers rather than condensed structures. On the other hand, it is known that such proteins (such as bacterial HU) strongly promote DNA ...

Many prokaryotic nucleoid proteins bend DNA and form extended helical protein-DNA fibers rather than condensed structures. On the other hand, it is known that such proteins (such as bacterial HU) strongly promote DNA ...

The DNA (Deoxyribonucleic Acid) is the molecule where the genetic information is codified. The sequences of different nitrogenous bases causes differences in the genomic expression, causing variance in the organisms. There ...

Homeostasis comprises the tendency of an organism or cell to regulate their chemical processes that take place internally so as to maintain health, vital functions and stability, owing to the coordinated response of its ...

The specific recognition of DNA binding sites by transcription factors (TFs) is key for the regulation of gene expression. However, most of TFs target short DNA sites and higher specificity is normally achieved by the ...

Background: Most of the Leishmania genome is reported to be constitutively expressed during the life cycle of the parasite, with a few regulated genes. Inter-species comparative transcriptomics evidenced a low number of ...

Immunohistochemical analysis of the p53 gene protein and cytometric assessment of nuclear DNA were performed in a series of 51 cases of intraductal breast proliferation. The series included 22 cases of intraductal hyperplasia ...

DNA methylation is dynamically modulated during postnatal brain development, and plays a key role in neuronal lineage commitment. This epigenetic mark has also recently been implicated in the development of neural sex ...

Sperm DNA quality and gene expression are crucial for early embryo development. Abnormal genomic processes can cause irreversible damage to totipotent cells, thereby altering the capacity for cell differentiation. ...