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Structural and Chemical Basis for Anticancer Activity of a Series of beta-Tubulin Ligands: Molecular Modeling and 3D QSAR Studies
(Soc Brasileira QuimicaSao PauloBrasil, 2009)
High 1,5-anti stereoinduction in boron-mediated aldol reactions of methyl ketones
(Amer Chemical SocWashingtonEUA, 2002)
Fragment-Based QSAR and Molecular Modeling Studies on a Series of Discodermolide Analogs as Microtubule-Stabilizing Anticancer Agents
(WILEY-V C H VERLAG GMBH, 2009)
Inhibition of microtubule function is an attractive rational approach to anticancer therapy. Although taxanes are the most prominent among the microtubule-stabilizers, their clinical toxicity, poor pharmacokinetic properties, ...
Structural and chemical basis for anticancer activity of a series of 'beta'-tubulin ligands: molecular modeling and 3D QSAR studies
(Sociedade Brasileira de Química, 2009)
An important approach to cancer therapy is the design of small molecule modulators that interfere with microtubule dynamics through their specific binding to the ²-subunit of tubulin. In the present work, comparative ...
Total synthesis of (-)-basiliskamide B
(Wiley-blackwellMaldenEUA, 2008)
Total Synthesis of Pteridic Acids A and B
(Amer Chemical SocWashingtonEUA, 2009)
Structural and chemical basis for anticancer activity of a series of²-tubulin ligands: molecular modeling and 3D QSAR studies
(Sociedade Brasileira de QuímicaBrasil, 2009)
Evaluación de la oferta natural y potencial de producción de (+)-discodermólido y/o análogos de la esponja marina del caribe colombiano Discodermia dissoluta
(2009)
La esponja marina Discodermia dissoluta es fuente del potente antimitótico (+)-discodermólido, útil para el tratamiento del cáncer. En este trabajo de maestría se estableció que la esponja marina Discodermia dissoluta ...