Artículos de revistas
Total synthesis of (-)-basiliskamide B
Registration in:
Advanced Synthesis & Catalysis. Wiley-blackwell, v. 350, n. 41858, n. 1017, n. 1021, 2008.
1615-4150
WOS:000255790100015
10.1002/adsc.200700589
Author
Dias, LC
Goncalves, CDS
Institutions
Abstract
The total synthesis of the polyketide antibiotic (-)-basiliskamide B is described. The convergent asymmetric synthesis relies on the use of a diastereoselective ethyl ketone aldol reaction followed by a syn selective reduction of a beta-hydroxy ketone and a Stille cross-coupling between a Z-vinylstannane and an E-vinyl iodide to establish the (Z,E)dienamide moiety. 350 41858 1017 1021