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Biliary drug excretion
(Springer, 2021)
Biliary excretion refers to the elimination of endogenous and exogenous compounds (and their metabolites) predominantly by secretion through the canalicular membrane into the canaliculus, a space formed between the apical ...
Drug Transporters
(Springer Nature Switzerland AG, 2018)
Membrane transporters perform a central function in many essential body functions, including traffic and compartmentalization of physiologic compounds, absorption of physiologic compounds (and, occasionally, structurally ...
Cholinesterase inhibitors for Alzheimer's disease: Multitargeting strategy based on anti-Alzheimer's drugs repositioning
(Bentham Science Publishers, 2019)
A research agenda for helminth diseases of humans: Intervention for control and elimination
(Public Library of Science, 2012)
Recognising the burden helminth infections impose on human populations, and particularly the poor, major intervention programmes have been launched to control onchocerciasis, lymphatic filariasis, soil-transmitted ...
Pharmacokinetics, safety, and tolerability of oxfendazole in healthy volunteers: A randomized, placebo-controlled first-inhuman single-dose escalation study
(American Society for Microbiology, 2019)
Cysticercosis is a parasitic disease that frequently involves the human central nervous system (CNS), and current treatment options are limited. Oxfendazole, a veterinary medicine belonging to the benzimidazole family of ...
Pharmacokinetic Profile of A New Diclofenac Prodrug without Gastroulcerogenic Effect
(2013-03-01)
Gastrotoxicity is a major problem for long-term therapy with non-steroidal anti-inflammatory drugs (NSAIDs). DICCIC (1-(2,6-dichlorophenyl)indolin-2-one) is a new diclofenac prodrug, which has proven anti-inflammatory ...
Pharmacokinetic Profile of A New Diclofenac Prodrug without Gastroulcerogenic Effect
(2013-03-01)
Gastrotoxicity is a major problem for long-term therapy with non-steroidal anti-inflammatory drugs (NSAIDs). DICCIC (1-(2,6-dichlorophenyl)indolin-2-one) is a new diclofenac prodrug, which has proven anti-inflammatory ...