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DNA-damaging activity of a cinnamate derivative and further compounds from Cinnamomum Australe (Lauraceae)
(Soc Brasileira Quimica, 2004-03-01)
The bioactive compound traps-3'-methylsulphonylallyl traps-cinnamate (1) along with the inactives iryelliptin (2) and (7R,8S,1'S)-Delta8-3',5'-dimethoxy-1',4'-dihydro-4'-oxo-7.0.2',8.1'-neolignan (3) were isolated from the ...
Acetylated DNA-damaging clerodane diterpenes from Casearia sylvestris
(Elsevier B.V., 1998-11-01)
In addition to the known diterpene casearin G (1), two new clerodane diterpene casearins type, casearin S (2) and casearin T (3), were isolated from an acetylated bioactive CH2Cl2/MeOH extract from leaves of Casealia ...
Acetylated DNA-damaging clerodane diterpenes from Casearia sylvestris
(Elsevier B.V., 1998-11-01)
In addition to the known diterpene casearin G (1), two new clerodane diterpene casearins type, casearin S (2) and casearin T (3), were isolated from an acetylated bioactive CH2Cl2/MeOH extract from leaves of Casealia ...
Contributions of DNA repair, cell cycle checkpoints and cell death to suppressing the DNA damage-induced tumorigenic behavior of Drosophila epithelial cells
(Nature Publishing Group, 2015-02)
When exposed to DNA-damaging agents, components of the DNA damage response (DDR) pathway trigger apoptosis, cell cycle arrest and DNA repair. Although failures in this pathway are associated with cancer development, the ...
Hyperglycemia differentially affects maternal and fetal DNA integrity and DNA damage response
(2016-02-12)
Objective: Investigate the DNA damage and its cellular response in blood samples from both mother and the umbilical cord of pregnancies complicated by hyperglycemia. Methods: A total of 144 subjects were divided into 4 ...
Genotoxicity of cigarette smoking in maternal and newborn lymphocytes
(Elsevier B.V., 2009-09-01)
Tobacco smoke contains a large number of substances known to induce DNA damage and to be hazardous to human health. Several reviews and meta-analyses have reported an association between maternal or paternal smoking habits ...
Genotoxicity of cigarette smoking in maternal and newborn lymphocytes
(Elsevier B.V., 2009-09-01)
Tobacco smoke contains a large number of substances known to induce DNA damage and to be hazardous to human health. Several reviews and meta-analyses have reported an association between maternal or paternal smoking habits ...
Derivado cinamoílico com atividade no reparo de DNA e outras substâncias de Cinnamomum australe (Lauraceae)
(Sociedade Brasileira de Química, 2004-04-01)
The bioactive compound trans-3'-methylsulphonylallyl trans-cinnamate (1) along with the inactives iryelliptin (2) and (7R,8S,1'S)-delta8'-3',5'-dimethoxy-1',4'-dihydro-4'-oxo-7.0.2',8.1'-neolignan (3) were isolated from ...
Derivado cinamoílico com atividade no reparo de DNA e outras substâncias de Cinnamomum australe (Lauraceae)
(Sociedade Brasileira de Química, 2004-04-01)
The bioactive compound trans-3'-methylsulphonylallyl trans-cinnamate (1) along with the inactives iryelliptin (2) and (7R,8S,1'S)-delta8'-3',5'-dimethoxy-1',4'-dihydro-4'-oxo-7.0.2',8.1'-neolignan (3) were isolated from ...
Study of DNA damage induced by dental bleaching agents in vitro
(2006-06-01)
Dental bleaching is a simple and conservative procedure for aesthetic restoration of vital and non-vital discolored teeth. Nevertheless, a number of studies have demonstrated the risk of tissue damage from the contact of ...