Derivado cinamoílico com atividade no reparo de DNA e outras substâncias de Cinnamomum australe (Lauraceae)

Artigo

Fecha

2004-04-01

Registro en:

Química Nova. Sociedade Brasileira de Química, v. 27, n. 2, p. 196-198, 2004.

0100-4042

http://hdl.handle.net/11449/26276

10.1590/S0100-40422004000200005

S0100-40422004000200005

S0100-40422004000200005.pdf

3310170899693944

4702004904231248

0037579054083160

4484083685251673

0000-0001-7616-9652

0000-0002-1516-7765

http://repositorioslatinoamericanos.uchile.cl/handle/2250/3899239

Autor

Universidade Estadual Paulista (Unesp)

Instituto de Botânica Secção de Fisiologia e Bioquímica de Plantas

Institución

Universidade Paulista Júlio de Mesquita Filho (Brasil)

Resumen

The bioactive compound trans-3'-methylsulphonylallyl trans-cinnamate (1) along with the inactives iryelliptin (2) and (7R,8S,1'S)-delta8'-3',5'-dimethoxy-1',4'-dihydro-4'-oxo-7.0.2',8.1'-neolignan (3) were isolated from the leaves of Cinnamomum australe. The structures of these compounds were assigned by analysis of 1D and 2D NMR data and comparison with data registered in the literature for these compounds. The DNA-damaging activity of 1 is being described for the first time.

Materias

Cinnamomum australe

Lauraceae

DNA-damaging activity

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