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Water regulation of actinomycin-D binding to DNA: The interplay among drug affinity, DNA long-range conformation, and hydration
(2000-01-01)
Actinomycin-D (actD) binds to natural DNA at two different classes of binding sites, weak and strong. The affinity for these sites is highly dependent on DNA sequence and solution conditions, and the interaction appears ...
Effects of caffeine on the structure and conformation of DNA: A force spectroscopy study
(International Journal of Biological Macromolecules, 2019)
Water regulation of actinomycin-D binding to DNA: the interplay among drug affinity, DNA long-range conformation, and hydration
(Wiley-Blackwell, 2000-01-01)
Actiaomycin-D (actD) binds to natural DNA at two different classes of binding sites, weak and strong. The affinity for these sites is highly dependent on DNA se(sequence and solution conditions, and the interaction appears ...
Water regulation of actinomycin-D binding to DNA: the interplay among drug affinity, DNA long-range conformation, and hydration
(Wiley-Blackwell, 2000-01-01)
Actiaomycin-D (actD) binds to natural DNA at two different classes of binding sites, weak and strong. The affinity for these sites is highly dependent on DNA se(sequence and solution conditions, and the interaction appears ...
An improved method to distinguish Entamoeba histolytica and Entamoeba dispar
(Cambridge Univ Press, 1999-10-01)
A 482 base pair gene fragment from samples of amoebae E. histolytica and E. dispar was amplified by PCR. the amplification products of fragments from the 2 species of amoebae presented differences in mobility in non-denaturing ...
Whydration effects on DNA double helix stability modulates ligand binding to natural DNA in response to changes in water activity
(Cellular & Molecular Biology, 2001-07-01)
In this work we present evidence that water molecules are actively involved on the control of binding affinity and binding site discrimination of a drug to natural DNA. In a previous study, the effect of water activity ...
Whydration effects on DNA double helix stability modulates ligand binding to natural DNA in response to changes in water activity
(Cellular & Molecular Biology, 2001-07-01)
In this work we present evidence that water molecules are actively involved on the control of binding affinity and binding site discrimination of a drug to natural DNA. In a previous study, the effect of water activity ...