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Streptonigrin induces delayed chromosomal instability involving interstitial telomeric sequences in Chinese hamster ovary cells

Mencucci, Maria Victoria; Vidal Bravo, Malena; Bianchi, Martha S.; Bolzan, Alejandro Daniel (Elsevier Science, 2012-08-30)

We analyzed the induction of chromosomal aberrations in Chinese hamster ovary (CHO) cells exposed to the radiomimetic compound streptonigrin (SN), in order to determine whether interstitial telomeric sequences (ITSs) are ...

Chromosomal Instability in Mouse Embryonic Fibroblasts Null for the Transcriptional Co-Repressor Ski

Marcelain Cubillos, Katherine; Armisen Yáñez, Ricardo; Aguirre, Adam; Ueki, Nobuhide; Toro, Jessica; Colmenares, Clemencia; Hayman, Michael J. (WILEY-BLACKWELL, 2012-01)

Ski is a transcriptional regulator that has been considered an oncoprotein given its ability to induce oncogenic transformation in avian model systems. However, studies in mouse and in some human tumor cells have also ...

Cytological characterization of an Aspergillus nidulans mutant from a strain with chromosomic duplication

GIANCOLI, Ágata Cristiane Huppert; AZEVEDO, João Lúcio de; KLEINER, Aline Aparecida (Sociedade Brasileira de Microbiologia, 2010)

A development mutant, named V103, was obtained spontaneously from the A strain of A. nidulans. The A strain contains a duplicated segment of chromosome I that has undergone translocation to chromosome II (I → II). ...

Genetic instability induced by low doses of x-rays in hamster cells

Seoane, Analia Isabel; Güerci, A.; Dulout, Fernando Noel (Taylor & Francis Ltd, 2007-12)

Purpose: Genomic instability involves time delayed events and can be manifested as elevated rates of heritable changes in the progeny of irradiated cells. To study the induction of chromosomal instability by very low doses ...

Clinical, Cytogenetic and Molecular Study in a Case of r(3) with 3p Deletion and Review of the Literature

Guilherme, R. Santos [UNIFESP]; Bragagnolo, S. [UNIFESP]; Pellegrino, R. [UNIFESP]; Christofolini, D. M.; Takeno, S. S. [UNIFESP]; Carvolheira, G. M. [UNIFESP]; Kulikowski, L. Domenici; Melaragno, M. I. [UNIFESP] (Karger, 2011-01-01)

Ring chromosome 3 is a rare abnormality with only 10 patients described in the literature. We report a patient with r(3) and similar to 6-Mb distal 3p deletion. Single nucleotide polymorphism array, multiplex ligation-dependent ...

Bleomycin induces delayed instability of interstitial telomeric sequences in Chinese hamster ovary cells

Vidal Bravo, Malena; Bianchi, Maria Martha; Bolzan, Alejandro Daniel (Elsevier Science, 2012-03)

We analyzed the behavior of interstitial telomeric sequences (ITSs) in the progeny of Chinese Hamster Ovary (CHO) cells exposed to the radiomimetic compound bleomycin (BLM) in order to determine if ITSs play some role in ...

Clinical, Cytogenetic, And Molecular Characterization Of Six Patients With Ring Chromosomes 22, Including One With Concomitant 22q11.2 Deletion

Guilherme R.S.; Soares K.C.; Simioni M.; Vieira T.P.; Gil-da-Silva-Lopes V.L.; Kim C.A.; Brunoni D.; Spinner N.B.; Conlin L.K.; Christofolini D.M.; Kulikowski L.D.; Steiner C.E.; Melaragno M.I. (Wiley-Liss Inc., 2014)

Cisplatin-induced Cytogenetic Alterations In V79 Cells

Goncalves E.M.; Dos Santos M.T.; Bertoncelli M.D.F.; Bussamara G.A.; Fuzzari T.; Lima V.A.; Pesotte L.C.; Pitori V.; Genari S.C. (, 2007)

Avaliação da instabilidade genômica em crianças com microcefalia do Rio Grande do Norte

Jordão, Larissa Alves (Universidade Federal do Rio Grande do NorteBrasilUFRNBiomedicina, 2019)

Descondensación de la heterocromatina en bovinos criollos portadores de la translocación robertsoniana (rob1; 29). acción del inductor 5 - azacitidina - C

Artigas, Rody; Iriarte, Wanda; De Soto, Leticia; Iriarte, Andrés; Llambí, Silvia; De Betancourth, Miguel; Postiglioni, Alicia (Universidad Nacional de Colombia Sede Palmira, 2008-01-01)

La translocación Robertsoniana (rob1; 29) está ampliamente distribuida en razas comerciales y en reservas genéticas de bovinos Criollos americanos. Se ha descrito un enlentecimiento en el desarrollo de embriones portadores ...