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Could dysregulation of RASSF1 expression be a mechanism of tumorigenesis in CTVT?
(Revista Pesquisa Veterinaria Brasileira, 2022-01-01)
Canine transmissible venereal tumor (CTVT) is the oldest known somatic cell lineage. It is a transmissible cancer that propagates naturally in dogs and reportedly contains gene mutations. RASSF1 participates in DNA damage ...
Cell-mediated immunity and expression of MHC class I and class II molecules in dogs naturally infected by canine transmissible venereal tumor: Is there complete spontaneous regression outside the experimental CTVT?
(2022-07-01)
The canine transmissible venereal tumor (CTVT) is a transplantable cancer with the ability evade the immune system, despite strict immune surveillance of the host; in this context, the relationship between inflammatory ...
Canine transmissible venereal tumors: Aspects related to programmed cell death
(2011-04-18)
Canine transmissible venereal tumor (CTVT) is a neoplasm transmitted by the physical transfer of viable tumor cells by direct contact with injured skin and/or mucous tissue. These cells can transpose across histocompatibility ...
Canine transmissible venereal tumors: Aspects related to programmed cell death
(2011-04-18)
Canine transmissible venereal tumor (CTVT) is a neoplasm transmitted by the physical transfer of viable tumor cells by direct contact with injured skin and/or mucous tissue. These cells can transpose across histocompatibility ...
Does the tumour microenvironment alter tumorigenesis and clinical response in transmissible venereal tumour in dogs?
(2018-09-01)
The canine transmissible venereal tumour (CTVT) is a transmissible cancer that is spread naturally between dogs, with the ability to develop and evade the immune system, despite strict immune surveillance of the host. ...
Evaluation of a genetic assay for canine transmissible venereal tumour diagnosis in Brazil
(Wiley-Blackwell, 2017-06-01)
The canine transmissible venereal tumour (CTVT) is a transmissible cancer that is spread between dogs by the allogeneic transfer of living cancer cells. The infectious agents in CTVT are the living cancer cells themselves, ...
Tumor venéreo transmissível canino - I. Expressão gênica e proteica e caracterização genotípica de DLADQA-1 (MHC-II); II. Estudo imuno-histoquímico da resposta imune local
(Universidade Estadual Paulista (Unesp), 2015-11-20)
The canine transmissible venereal tumor (CTVT) is a transmissible cancer that is spread between dogs by the allogeneic transfer of living cancer cells during coitus. It is the oldest cancer lineage known in nature and one ...
The role of the multi-drug resistance 1, p53, b cell lymphoma 2, and bcl 2-associated X genes in the biologic behavior and chemotherapeutic resistance of canine transmissible venereal tumors
(2019-12-01)
Background: Canine transmissible venereal tumors (CTVTs) generally have different cytomorphologic subtypes and phases of progression. Some tumors have variable biologic behavior including a progressive increase in tumor ...
Immunophenotypic and molecular profile of cancer stem-cell markers in ex vivo canine transmissible venereal tumour (CTVT)
(Wiley-Blackwell, 2022-09-13)
Background: Several studies have attempted to characterise the origin of canine transmissible venereal tumour (CTVT). However, the participation of cancer stem cells (CSC) has not been reported Objectives: Herein we describe ...