Artículos de revistas
Canine transmissible venereal tumors: Aspects related to programmed cell death
Fecha
2011-04-18Registro en:
Brazilian Journal of Veterinary Pathology, v. 4, n. 1, p. 67-75, 2011.
1983-0246
2-s2.0-79953882443
6404176495306171
Autor
Universidade Estadual Paulista (Unesp)
Institución
Resumen
Canine transmissible venereal tumor (CTVT) is a neoplasm transmitted by the physical transfer of viable tumor cells by direct contact with injured skin and/or mucous tissue. These cells can transpose across histocompatibility barriers into unrelated hosts. This review focuses on the biology of apoptosis and the interaction of proteins involved in this process, as well as p53, p63 and the antiapoptotic protein Bcl-2. As such, this disease offer unique opportunity to study the biology of transplantable tumours and the interaction of proteins involved in apoptosis process and the prognosis of CTVT.