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The corticotropin-releasing hormone network and the hypothalamic-pituitary- adrenal axis: Molecular and cellular mechanisms involved
(Karger, 2011-07)
Corticotropin-releasing hormone (CRH) plays a key role in adjusting the basal and stress-activated hypothalamic-pituitary-adrenal axis (HPA). CRH is also widely distributed in extrahypothalamic circuits, where it acts as ...
Divergent Roles of the CRH Receptors in the Control of Gonadotropin Secretion Induced by Acute Restraint Stress at Proestrus
(ENDOCRINE SOCCHEVY CHASE, 2012)
CRH has been implicated as a mediator of stress-induced effects on the hypothalamus-pituitary-gonad axis, acting via CRH receptors in various brain regions. We investigated whether the effects of restraint stress on the ...
Deletion of CRH From GABAergic Forebrain Neurons Promotes Stress Resilience and Dampens Stress-Induced Changes in Neuronal Activity
(Frontiers Media Sa, 2019-09-20)
Dysregulation of the corticotropin-releasing hormone (CRH) system has been implicated in stress-related psychopathologies such as depression and anxiety. Although most studies have linked CRH/CRH receptor 1 signaling to ...
Hyperglycemia induced by acute central fluoxetine administration: role of the central CRH system and 5-HT3 receptors
(Elservier, 2004)
Brain serotonin and CRH systems participate in the control of blood glucose levels. We have previously demonstrated that the
pharmacological stimulation of central 5-HT3 receptors, the target for several therapeutic agents ...
Endocrinology and the brain: Corticotropin-Releasing Hormone signaling
(BioScientifica, 2017-07-14)
Corticotropin-releasing hormone (CRH) is a key player of basal and stress activated responses in the hypothalamic-pituitary-adrenal axis (HPA) and in extrahypothalamic circuits, where it functions as a neuromodulator to ...
Interacción molecular de los receptores CRH-R2 y DA-D1 en el área tegmental ventral de rata.
(2013)
La administración repetida de drogas de abuso genera cambios plásticos perdurables que se traducen en alteraciones en las propiedades funcionales de las neuronas del sistema mesocorticolímbico, como lo es la sensibilización ...
Role of the hypothalamic pituitary adrenal axis in the control of the response to stress and infection
(Associação Brasileira de Divulgação Científica, 2000-10)
The release of adrenocorticotropin (ACTH) from the corticotrophs is controlled principally by vasopressin and corticotropin-releasing hormone (CRH). Oxytocin may augment the release of ACTH under certain conditions, whereas ...