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Mechanisms of copper homeostasis in bacteria
(Frontiers, 2013-11)
Copper is an important micronutrient required as a redox co-factor in the catalytic centers of enzymes. However, free copper is a potential hazard because of its high chemical reactivity. Consequently, organisms exert a ...
Summary of the Third International Workshop on Iron and Copper Homeostasis
(Sociedad de Biología de Chile, 2006)
Understanding copper homeostasis in humans and copper effects on health
(Sociedad de Biología de Chile, 2006)
Compartment and signal-specific codependence in the transcriptional control of Salmonella periplasmic copper homeostasis
(National Academy of Sciences, 2016-10)
Copper homeostasis is essential for bacterial pathogen fitness and infection, and has been the focus of a number of recent studies. In Salmonella, envelope protection against copper overload and macrophage survival depends ...
Gene expression profiling in wild-type and metallothionein mutant fibroblast cell lines
(2006)
The role of metallothioneins (MT) in copper homeostasis is of great interest, as it appears to be partially
responsible for the regulation of intracellular copper levels during adaptation to extracellular excess of ...
Overexpression of amyloid precursor protein increases copper content in HEK293 cells
(2009)
Amyloid precursor protein (APP) is a transmembrane glycoprotein widely expressed in mammalian tissues and plays a central role in Alzheimer’s disease. However, its physiological function remains elusive. Cu2+ binding and ...
CutC is induced late during copper exposure and can modify intracellular copper content in Enterococcus faecalis
(Elsevier, 2011)
Copper is a micronutrient that is required for proper metabolic functioning of most prokaryotic and
eukaryotic organisms. To sustain an adequate supply of copper, a cell requires molecular mechanisms
that control the ...
Interplay between copper and zinc homeostasis through the transcriptional regulator Zur in Enterococcus faecalis.
(2015)
By integrating the microarray expression data and a global E. faecalis transcriptional network we identified a sub-network activated by zinc and copper. Our analyses indicated that the transcriptional response of the ...