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In vitro characterization of coevaporates containing chitosan for colonic drug delivery
(Elsevier B.V., 2009-10-15)
A relative simple drug delivery system in the form of coevaporates were prepared and analyzed. They were based on chitosan (CS), a polysaccharide that undergoes specific degradation by colonic enzymes. Enteric polymers, ...
In vitro characterization of coevaporates containing chitosan for colonic drug delivery
(Elsevier B.V., 2009-10-15)
A relative simple drug delivery system in the form of coevaporates were prepared and analyzed. They were based on chitosan (CS), a polysaccharide that undergoes specific degradation by colonic enzymes. Enteric polymers, ...
Understanding the role of colon-specific microparticles based on retrograded starch/pectin in the delivery of chitosan nanoparticles along the gastrointestinal tract
(2021-01-01)
The encapsulation of nanoparticles within microparticles designed for specific delivery to the colon is a relevant strategy to avoid premature degradation or release of nanoparticles during their passage through the stomach ...
Cellulose nanofibers improve the performance of retrograded starch/pectin microparticles for colon-specific delivery of 5-ASA
(2021-09-01)
Cellulose nanofibers (CNF) were employed as the nanoreinforcement of a retrograded starch/pectin (RS/P) excipient to optimize its colon-specific properties. Although starch retrogra-dation ranged from 32 to 73%, CNF addition ...
Oral delivery of micro/nanoparticulate systems based on natural polysaccharides for intestinal diseases therapy: Challenges, advances and future perspectives
(2021-06-10)
Colon-targeted oral delivery of drugs remains as an appealing and promising approach for the treatment of prevalent intestinal diseases (ID), such as inflammatory bowel disease (IBD) and colorectal cancer (CRC). Notwithstanding, ...
In vitro characterization of coevaporates containing chitosan for colonic drug delivery
(Elsevier B.V., 2014)
Chitosan-pectin multiparticulate systems associated with enteric polymers for colonic drug delivery
(Elsevier B.V., 2010-10-15)
The great challenge in using native degradable polysaccharides for the development of drug delivery systems is their high aqueous solubility, which may contribute to the undesirable premature and localized release of the ...
Chitosan-pectin multiparticulate systems associated with enteric polymers for colonic drug delivery
(Elsevier B.V., 2010-10-15)
The great challenge in using native degradable polysaccharides for the development of drug delivery systems is their high aqueous solubility, which may contribute to the undesirable premature and localized release of the ...