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Molecular modeling and UV-vis spectroscopic studies on the mechanism of action of reversed chloroquine (RCQ)

OTELO, Vanessa A.; SANT`ANA, Antonio C.; FARIA, Dalva L. A. de; MENEZES, Carla M. S. (PERGAMON-ELSEVIER SCIENCE LTD, 2011)

Reversed chloroquine (RCQ) is a multiple ligand compound active against chloroquine-sensitive and resistant falciparum malaria. It is composed by a 4-aminoquinoline moiety (like that present in chloroquine (CQ)) joined to ...

Platinum(ii)-chloroquine complexes are antimalarial agents against blood and liver stages by impairing mitochondrial function

Macedo, Taís Soares; Villarreal, Wilmer Jose; Couto, Camila C; Moreira, Diogo Rodrigo de Magalhães; Navarro, Maribel; Machado, Marta; Prudêncio, Miguel; Batista, Alzir Azevedo; Soares, Milena Botelho Pereira (Royal Society of Chemistry, 2018)

Chloroquine: Modes Of Action Of An Undervalued Drug.

Thomé, Rodolfo; Lopes, Stefanie Costa Pinto; Costa, Fabio Trindade Maranhão; Verinaud, Liana (2013)

In vivo and in vitro antimalarial effect and toxicological evaluation of the chloroquine analogue PQUI08001/06

Reis, Patricia Alves; Pais, Karla Ceodaro; Pereira, Monica Farah; Douradinha, Bruno; Costa, Natália Ferreira; Kaiser, Carlos Roland; Bozza, Patricia Torres; Areas, André Luiz Lisboa; Zalis, Mariano Gustavo; Ferreira, Marcelle de Lima; Souza, Marcos Vinícius Nora de; Frutuoso, Valber da Silva; Faria Neto, Hugo C. de Castro (Springer Verlag (Germany), 2019)

Chloroquine analogs as antimalarial candidates with potent in vitro and in vivo activity

Aguiar, Anna Caroline Campos; Murce, Erika; Cortopassi, Wilian Augusto; Pimentel, Andre Silva; Almeida, Maria M. F. S.; Barros, Daniele C. S.; Guedes, Jéssica S.; Meneghetti, Mauro Roberto; Krettli, Antoniana Ursine (Elsevier, 2019)

Fighting Plasmodium chloroquine resistance with acetylenic chloroquine analogues

Cortopassi, Wilian Augusto; Gunderson, Emma; Annunciato, Yasmin; Silva, Antony E S; Ferreira, Amália Dos Santos; Teles, Carolina Bioni Garcia; Pimentel, Andre S; Ramamoorthi, Roopa; Gazarini, Marcos L; Meneghetti, Mario R; Guido, Rafael V C; Pereira, Dhelio Batista; Jacobson, Matthew P; Krettli, Antoniana Ursine; Aguiar, Anna Caroline Campos (Elsevier, 2023)

Iloneoside, an antimalarial pregnane glycoside isolated from Gongronema latifolium leaf, potentiates the activity of chloroquine against multidrug resistant Plasmodium falciparum.

Adebayo, J. O.; Cerávolo, Isabela Penna; Gyebi, G. A.; Olorundare, O. E.; Babatunde, A. S.; Coutinho, Julia Penna; Koketsu, M.; Krettli, Antoniana Ursine (Elsevier/North-Holland Biomedical Press, 2022)

Genetic diversity of chloroquine-resistant Plasmodium vivax parasites from the western Brazilian Amazon

Lizcano, Omaira Vera; Resende, Sarah Stela; Melo, Yonne Francis Chehuan; Lacerda, Marcus Vinicius Guimarães de; Brito, Cristiana Ferreira Alves de; Zalis, Mariano Gustavo (Fundação Oswaldo Cruz, 2015)

Antiplasmodial activity of chloroquine analogs against chloroquine-resistant parasites, docking studies and mechanisms of drug action

Souza, Nicolli Bellotti de; Carmo, Arturene Maria Lino; Silva, Adilson David de; França, Tanos Celmar Costa; Krettli, Antoniana Ursine (Biomed Central Ltda, 2014)

Antimalarial effect in vitro and lack of modulating effect of desipramine and imipramine

Universidade de São Paulo (USP); Universidade Estadual Paulista (Unesp); Superintendencia Controle Endemias (Royal Soc Tropical Medicine, 1997-11-01)

Based on previous studies in vitro of the modulating effect of desipramine on chloroquine-resistance of Plasmodium falciparum, the effect of desipramine and imipramine on freshly isolated resistant Brazilian strains of the ...

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