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Inhibition of tau phosphorylating protein kinase cdk5 prevents β-amyloid-induced neuronal death
(1999)
The key target of this study was the tau protein kinase II system (TPK II) involving the catalytic subunit cdk5 and the regulatory component p35. TPK II is one of the tau phosphorylating systems in neuronal cells, thus ...
Evidence for the participation of the neuron-specific CDK5 activator p35 during laminin-enhanced axonal growth
(1998)
Cultures of cerebellar macroneurons were used to study the pattern of expression, subcellular localization, and function of the neuronal cdk5 activator p35 during laminin-enhanced axonal growth. The results obtained indicate ...
Mitochondrial ncRNA targeting induces cell cycle arrest and tumor growth inhibition of MDA-MB-231 breast cancer cells through reduction of key cell cycle progression factors
(2019)
The family of long noncoding mitochondrial RNAs (ncmtRNAs), comprising sense (SncmtRNA), and antisense (ASncmtRNA-1 and ASncmtRNA-2) members, are differentially expressed according to cell proliferative status; SncmtRNA ...
Stathmin 1 In Normal And Malignant Hematopoiesis
(The Biochemical Society of the Republic of Korea, 2014)
Evaluación de miRNAs en la línea celular de melanoma B16 inducida a pigmentación diferencial y disminución del crecimiento celular por la L-Tirosina y la 5-bromo-2´-deoxiuridina
(Bogotá - Medicina - Doctorado en Ciencias BiomédicasUniversidad Nacional de Colombia - Sede Bogotá, 2020-12-04)
miRNAs are small non-coding RNAs associated with post-transcriptional gene regulation in melanoma, a cancer of melanocytes, cells specialized in melanin synthesis. The present work aimed to evaluate the differential ...