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Cardiac involvement in recovered COVID-19 patients identified by magnetic resonance imaging
Objective: To evaluate cardiac involvement in recovered COVID-19 patients using cardiac
MRI.
Background: Myocardial injury caused by COVID-19 was previously reported in
hospitalized patients. It is unknown if there is ...
The Role of Oxidative Stress in the Aging Heart
(2022-02-01)
Medical advances and the availability of diagnostic tools have considerably increased life expectancy and, consequently, the elderly segment of the world population. As age is a major risk factor in cardiovascular disease ...
Eccentric and concentric cardiac hypertrophy induced by exercise training: microRNAs and molecular determinants
(Associação Brasileira de Divulgação Científica, 2011)
Among the molecular, biochemical and cellular processes that orchestrate the development of the different phenotypes of cardiac hypertrophy in response to physiological stimuli or pathological insults, the specific ...
Pro-fibrotic effect of oxidized LDL in cardiac myofibroblasts
(Elsevier, 2020)
Inflammatory signals associated with cardiac diseases trigger trans-differentiation of cardiac fibroblasts to cardiac myofibroblasts. Cardiac myofibroblasts are the main cell type involved in the development of cardiac ...
Effects of obesity on the cardiac proteome
(2021-03-31)
Obesity has reached epidemic proportions in both developed and developing countries. It is currently recognized as a major health concern due to excessive adipose tissue which is associated with a wide range of other medical ...
Blockage of Angiotensin II type 2 receptor prevents thyroxine-mediated cardiac hypertrophy by blocking Akt activation
(DR DIETRICH STEINKOPFF VERLAG, 2010)
Although most of effects of Angiotensin II (Ang II) related to cardiac remodelling can be attributed to type 1 Ang II receptor (AT(1)R), the type 2 receptor (AT(2)R) has been shown to be involved in the development of some ...
Erdheim-Chester disease. Report of one case
(SOC MEDICA SANTIAGO, 2011)
We report a 76-year-old male who was admitted due to progressive congestive heart failure lasting several months. An echocardiogram showed a large pericardial effusion with early signs of pericardial tamponade and an ...
Phospholamban: a tiny protein with a prominent role in the regulation of cardiac relaxation and contractility
(SAFIS, 2010-11)
Phospholamban (PLN) is a small sarcoplasmic reticulum (SR) protein that in the dephosphorylated state tonically inhibits the SR Ca2+-ATPase (SERCA2a). Different type of evidence to be described, points to PLN as a crucial ...
Cardiac Remodeling Induced by All-Trans Retinoic Acid is Detrimental in Normal Rats
(2017-11-01)
Background/Aims: This study aimed to discern whether the cardiac alterations caused by retinoic acid (RA) in normal adult rats are physiologic or pathologic. Methods and Results: Wistar rats were assigned into four groups: ...
Regulation of the Cardiac Sodium/Bicarbonate cotransporter by Angiotensin II: potential contribution to structural, ionic and electrophysiological Myocardial remodelling
(Bentham Science Publishers, 2013-02)
The sodium/ bicarbonate cotransporter (NBC) is, with the Na+ /H+ exchanger (NHE), an important alkalinizing mechanism that maintains cellular intracellular pH (pHi). In the heart exists at least three isoforms of NBC, one ...