Large conductance calcium- and voltage-sensitive K+ (MaxiK) channels share properties of voltage- and ligand-gated ion channels. In voltage-gated channels, membrane depolarization promotes the displacement of charged ...

Using Ba2 1 as a probe, we performed a detailed characterization of an external K 1 binding site located in the pore of a large conductance Ca2 1-activated K 1 (BKCa) channel from skeletal muscle incorporated into planar ...

Large conductance calcium- and voltage-sensitive K+ (MaxiK) channels share properties of voltage-and ligand-gated ion channels. In voltage-gated channels, membrane depolarization promotes the displacement of charged residues ...

Shaker K+ channels inactivate through two distinct molecular mechanisms: N-type, which involves the N-terminal domain and C-type that appears to involve structural modifications at the external mouth of the channel. We ...

This introductory minireview points out the importance of ion channels for cell communication. The basic concepts on the structure and function of ion channels triggered by membrane voltage changes, the so-called voltage-gated ...

Some K+ channels can be activated by a rise in cytosolic Ca2+ and, in two cases (the K+ channels from the archeon Methanobacterium thermoautotrophicum (MthK) and the large conductance voltage- and Ca2+-activated K+ (BK) ...

Myotonic muscular dystrophy is a genetic disease characterized mainly by muscle atrophy and myotonia, a repetitive electrical activity of muscle. In the present study, the possible role of apamin‐sensitive K+ channels in ...

Aims: To examine the vasodilatation induce by the NO donors, [Ru(terpy)(bdq)NO]3+ (TERPY) and sodium nitroprusside (SNP), and to compare their effects in aortic rings from hypertensive 2K-1C and normotensive 2K rats. Main ...