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The CREB-binding protein (CBP) cooperates with the serum response factor for transactivation of the c-fos serum response element
The serum response element is one of the major promoter elements of the immediate early response to extracellular signals. The serum response element includes two main binding sites for proteins: the Ets box, which binds ...
IGF-1 protects cardiac myocytes from hyperosmotic stress-induced apoptosis via CREB
(ACADEMIC PRESS INC ELSEVIER SCIENCE, 2005-11-04)
Hyperosmotic stress stimulates a rapid and pronounced apoptosis in cardiac myocytes which is attenuated by insulin-like growth factor-1 (IGF-1). Because in these cells IGF-1 induces intracellular Ca2+ increase, we assessed ...
Transcription Factor CREB3L1 Regulates Vasopressin Gene Expression in the Rat Hypothalamus
(Soc Neuroscience, 2014-03-12)
Arginine vasopressin (AVP) is a neurohypophysial hormone regulating hydromineral homeostasis. Here we show that the mRNA encoding cAMP responsive element-binding protein-3 like-1 (CREB3L1), a transcription factor of the ...
The camp response element binding protein (creb) is activated by insulin-like growth factor-1 (igf-1) and regulates myostatin gene expression in skeletal myoblast
(ACADEMIC PRESS INC ELSEVIER SCIENCE, 2013)
Oxidative stress-induced CREB upregulation promotes DNA damage repair prior to neuronal cell death protection
(Springer, 2017-01)
cAMP response element-binding (CREB) protein is a cellular transcription factor that mediates responses to different physiological and pathological signals. Using a model of human neuronal cells we demonstrate herein, that ...
XTIF2, a Xenopus homologue of the human transcription intermediary factor, is required for a nuclear receptor pathway that also interacts with CBP to suppress Brachyury and XMyoD
(2000)
Ligand-bound nuclear receptors (NRs) recruit cofactors such as members of the p160 family and CREB-binding protein (CBP) to activate transcription. We have cloned the Xenopus homologue of the human transcription intermediary ...
Stress induces behavioral sensitization, increases nicotine-seeking behavior and leads to a decrease of CREB in the nucleus accumbens
(Pergamon-Elsevier B.V. Ltd, 2012-05-01)
Experimental evidence shows that exposure to stress engenders behavioral sensitization and increases drug-seeking and leads to intense drug taking. However the molecular mechanisms involved in these processes is not well ...