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CK2α/CK1α chimeras are sensitive to regulation by the CK2β subunit
(2008)
The effect of CK2β on the activity of CK2α and other protein kinases that can bind this regulatory subunit is not fully understood. In an attempt to improve our understanding of this effect, chimeras of CK2α and CK1α have ...
CK2 alpha/CK1 alpha chimeras are sensitive to regulation by the CK2 beta subunit
(Springer, 2008)
The effect of CK2 beta on the activity of CK2 alpha and other protein kinases that can bind this regulatory subunit is not fully understood. In an attempt to improve our understanding of this effect, chimeras of CK2 alpha ...
An inactive mutant of the α subunit of protein kinuse CK2 that traps the regulatory CK2β subunit
(1997)
Protein kinase CK2 (casein kinase 2) is a ubiquitous Ser/Thr protein kinase involved in cell proliferation. Mutation of the α subunit of the Xenopus laevis CK2 to change aspartic acid 156 to alanine (CK2αA156) resulted in ...
Promiscuous subunit interactions: A possible mechanism for the regulation of protein kinase CK2
(1998)
Protein kinase CK2 is a ubiquitous eukaryotic ser/thr protein kinase. The active holoenzyme is a heterotetrameric protein corn posed of catalytic (α and α') and regulatory (β) subunits that phosphorylates many different ...
Differential localization of α' and β subunits of protein kinase CK2 during rat spermatogenesis
(2009)
Protein kinase CK2 is a serine/threonine kinase expressed in organisms from yeast to human and is composed of a catalytic subunit (α or α') and a regulatory subunit (β) forming a holoenzyme with the possible subunit ...
Cloning, expression and properties of the α' subunit of case in kinase 2 from zebrafish (Danio rerio)
(Blackwell Publishing Ltd, 1996)
The protein kinase casein kinase 2 (CK2) is ubiquitous in eukaryotic cells and is apparently involved in the control of cell division. The holoenzyme is a tetramer composed of two catalytic subunits (α and/or α') and ...
T. cruzi DNA polymerase beta (Tcpol beta) is phosphorylated in vitro by CK1, CK2 and TcAUK1 leading to the potentiation of its DNA synthesis activity
(Public Library Science, 2021)
The unicellular protozoan Trypanosoma cruzi is the causing agent of Chagas disease which
affects several millions of people around the world. The components of the cell signaling
pathways in this parasite have not been ...
Autophosphorylation of carboxy-terminal residues inhibits the activity of protein kinase CK1α
(2009)
CK1 constitutes a protein kinase subfamily that is involved in many important physiological processes. However, there is limited knowledge about mechanisms that regulate their activity. Isoforms CK1δ and CKlε were previously ...
Protein kinase CK2 as an ectokinase: The role of the regulatory CK2 beta subunit
(NATL ACAD SCIENCES, 2008-04-15)
Protein kinase CK2 (also known as casein kinase 2) is present in the
cytoplasm, nuclei, and several other organelles. In addition, this
enzyme has been found bound to the external side of the cell
membrane where it acts ...