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Free cholesterol and cholesterol esters in bovine oocytes: Implications in survival and membrane raft organization after cryopreservation
(Public Library of Science, 2017-07-07)
Part of the damage caused by cryopreservation of mammalian oocytes occurs at the plasma membrane. The addition of cholesterol to cell membranes as a strategy to make it more tolerant to cryopreservation has been little ...
Cholesterol Depletion Disorganizes Oocyte Membrane Rafts Altering Mouse Fertilization
(Public Library of Science, 2013-04-25)
Drastic membrane reorganization occurs when mammalian sperm binds to and fuses with the oocyte membrane. Two oocyte protein families are essential for fertilization, tetraspanins and glycosylphosphatidylinositol-anchored ...
Procyanidins can interact with Caco-2 cell membrane lipid rafts: involvement of cholesterol
(Elsevier Science, 2013-11)
Large procyanidins (more than three subunits) are not absorbed at the gastrointestinal tract but could exert local effects through their interactions with membranes. We previously showed that hexameric procyanidins (Hex), ...
Localization of the Sodium-Taurocholate cotransporting polypeptide in membrane rafts and modulation of its activity by cholesterol in vitro
(ELSEVIER SCIENCE BV, 2008)
Background: The relevance of discrete localization of hepatobiliary transporters in specific membrane microdomains is not well known. Aim: To determine whether the Na+/taurocholate cotransporting polypeptide (Ntcp), the ...
Transmembrane domain dimerization induces cholesterol rafts in curved lipid bilayers
(Royal Society of Chemistry, 2019-01)
Are the dimerization of transmembrane (TM) domains and the reorganization of the lipid bilayer two independent events? Does one event induce or interfere with the other? In this work, we have performed well-tempered ...
Free cholesterol and cholesterol esters in bovine oocytes: Implications in survival and membrane raft organization after cryopreservation
(2017)
Part of the damage caused by cryopreservation of mammalian oocytes occurs at the plasma
membrane. The addition of cholesterol to cell membranes as a strategy to make it more tolerant
to cryopreservation has been little ...
Detergent resistant domains in erythrocyte membranes survive after cell cholesterol depletion: an EPR spin label study
(Elsevier Ireland, 2003-12)
We use electron paramagnetic resonance (EPR) with liposoluble spin labels in order to study the lipid structures obtained after Triton X-100 extraction of erythrocyte membranes. The apparent order profile in these detergent ...
Unraveling the role of membrane microdomains during microbial infections
(Springer, 2017-10)
Infectious diseases pose major socioeconomic and health-related threats to millions of people across the globe. Strategies to combat infectious diseases derive from our understanding of the complex interactions between the ...
Cholesterol depletion induces PKA-mediated basolateral-to-apical transcytosis of the scavenger receptor class B type I in MDCK cells
(NATL ACAD SCIENCES, 2004)
Cholesterol-based membrane microdomains, or lipid rafts, are believed to play important, yet poorly defined, roles in protein trafficking and signal transduction. In polarized epithelial cells, the current view is that ...
Structure and dynamics of nano-sized raft-like domains on the plasma membrane
(American Institute of Physics, 2012-01)
Cell membranes are constitutively composed of thousands of different lipidic species, whose specific organization leads to functional heterogeneities. In particular, sphingolipids, cholesterol and some proteins associate ...