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Expression of a plastid-targeted flavodoxin decreases chloroplast reactive oxygen species accumulation and delays senescence in aging tobacco leaves
(Frontiers Research Foundation, 2018-07)
Leaf senescence is a concerted physiological process involving controlled degradation of cellular structures and reallocation of breakdown products to other plant organs. It is accompanied by increased production of reactive ...
Potato Virus X Coat Protein Fusion to Human Papillomavirus 16 E7 Oncoprotein Enhance Antigen Stability and Accumulation in Tobacco Chloroplast
(Springer, 2009-11)
Cervical cancer linked to infection with human papillomavirus (HPV) is the third cause of cancer-related death in women. As the virus cannot be propagated in culture, vaccines have been based on recombinant antigens with ...
Structural features and transcript-editing analysis of sugarcane (Saccharum officinarum L.) chloroplast genome
(SpringerNew YorkEUA, 2004)
The fusion of Toxoplasma gondii SAG1 vaccine candidate to Leishmania infantum heat shock protein 83-kDa improves expression levels in tobacco chloroplasts
(Wiley, 2015-05)
Chloroplast transformation technology has emerged as an alternative platform offering many advantages over nuclear transformation. SAG1 is the main surface antigen of the intracellular parasite Toxoplasma gondii and a ...
Over-accumulation of astaxanthin in Haematococcus pluvialis through chloroplast genetic engineering
(Elsevier, 2018)
The carotenoid biosynthesis pathway of Haematococcus pluvialis has been genetically modified to overproduce astaxanthin, a red pigment of high commercial value. The endogenous phytoene desaturase coding sequence (pds) has ...
A chloroplast-derived Toxoplasma gondii GRA4 antigen used as an oral vaccine protects against toxoplasmosis in mice
(Wiley Blackwell Publishing, Inc, 2012-12)
The parasitic protozoan Toxoplasma gondii, the causal agent of toxoplasmosis, can infect most mammals and birds. In human medicine, T. gondii can cause complications in pregnant women and immunodeficient individuals, while ...