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Stereoselective analysis of carvedilol in human plasma and urine using HPLC after chiral derivatization
(John Wiley & Sons Ltd, 2008-07-01)
An enantioselective high-performance liquid chromatographic method for the analysis of carvedilol in plasma and urine was developed and validated using (-)-menthyl chloroformate (MCF) as a derivatizing reagent. Chloroform ...
Anti-inflammatory potential of a carvedilol gel in the pulpal tissue of rats after dental bleaching: A histopathological evaluation
(2019-05-01)
AIM: Carvedilol is an antioxidant that decreases inflammation in periodontitis. The hydrogen peroxide (H2 O2 ) of bleaching gel causes inflammation and necrosis of the dental pulp. In the present study, we evaluated the ...
Carvedilol estudos de estabilidade e perfil de dissolução
(Universidade Federal de Santa MariaBRFarmáciaUFSMPrograma de Pós-Graduação em Ciências Farmacêuticas, 2007-12-17)
The aim of the present study was to evaluate the stability of the active principal ingredient of carvedilol, and the release of the drug in vitro, through studies of dissolution. In the stability
study were used hydrolytic ...
Pharmacokinetic and pharmacodynamic properties of carvedilol in fructose hypertensive rats
(Taylor & Francis, 2011-09)
The cardiovascular effects and mechanism of antihypertensive response of carvedilol were assessed in fructose fed rats using pharmacokinetic–pharmacodynamic (PK-PD) modelling. Male Sprague Dowley rats were randomly divided ...
Stereoselective analysis of carvedilol in human plasma and urine using HPLC after chiral derivatization
(JOHN WILEY & SONS LTD, 2008)
An enantioselective high-performance liquid chromatographic method for the analysis of carvedilol in plasma and urine was developed and validated using (-)-menthyl chloroformate (MCF) as a derivatizing reagent. Chloroform ...
Stereoselective analysis of carvedilol in human plasma and urine using HPLC after chiral derivatization
(John Wiley & Sons Ltd, 2008-07-01)
An enantioselective high-performance liquid chromatographic method for the analysis of carvedilol in plasma and urine was developed and validated using (-)-menthyl chloroformate (MCF) as a derivatizing reagent. Chloroform ...
Impacto do Carvedilol no perfil lipídico de pacientes com insuficiência cardíaca
(2013-01-22)
IMPACTO DO CARVEDILOL NO PERFIL LIPÍDICO DE PACIENTES COM INSUFICIÊNCIA CARDÍACA. Introdução: A insuficiência cardíaca (IC) é uma síndrome frequente em nosso meio e é associada a uma significativa mortalidade e morbidade. ...
Stereoselective analysis of carvedilol in human plasma and urine using HPLC after chiral derivatization
(John Wiley & Sons Ltd, 2014)
Analysis of carvedilol enantiomers in human plasma using chiral stationary phase column and liquid chromatography with tandem mass spectrometry
(WILEY-BLACKWELLMALDEN, 2012)
Carvedilol is an antihypertensive drug available as a racemic mixture. (-)-(S)-carvedilol is responsible for the nonselective beta-blocker activity but both enantiomers present similar activity on a1-adrenergic receptor. ...