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Interaction between the C-Terminal Peptides of Tubulin and Tubulin S Detected with the Fluorescent Probe 4',6-Diamidino-2-Phenylindole
(1993)
The digestion of tubulin with subtilisin and the reassociation of the digestion products was followed by means of the fluorescent probe 4',6-diamidino-2-phenylindole (DAPI). The fluorescence spectra of DAPI bound to chicken ...
Helicity of α(404-451) and β(394-445) tubulin C-terminal recombinant peptides
(1999)
We have investigated the solution conformation of the functionally relevant C-terminal extremes of α- and β-tubulin, employing the model recombinant peptides RL52α3 and RL33β6, which correspond to the amino acid sequences ...
Carboxyl terminal sequences of β-tubulin involved in the interaction of HMW-MAPs. Studies using site-specific antibodies
(Kluwer Academic Publishers, 1994)
After the finding of the involvement of the C-terminal moieties of tubulin subunits in the interaction of MAPs, different studies have focused on the substructure of the binding domains for the different MAPs. Current ...
Specific macromolecular interactions between tau and the microtubule system
(Kluwer Academic Publishers, 1992)
The microtubule-associated protein Tau, a major component of brain microtubules, shares common repeated C-terminal sequences with the high molecular-weight protein MAP-2. It has been shown that tau peptides V187-G204 and ...
Purification and characterization of the high molecular weight microtubule associated proteins from neonatal rat brain
(Kluwer Academic Publishers, 1994)
The changes in the levels of microtubule-associated proteins (MAPs) during advanced embryonic stages, neonatal and adult organisms reflect the importance of these cytoskeletal proteins in relation to the morphogenesis of ...
A Novel Monoclonal Antibody Against the C-terminus of beta-Tubulin Recognizes Endocytic Organelles in Trypanosoma cruzi
(Bentham Science Publ Ltd, 2012-06-01)
Microtubule cytoskeleton is a dynamic structure involved in the maintenance of eukaryote cell shape, motion of cilia and flagellum, and intracellular movement of vesicles and organelles. Many antibodies against tubulins ...
Estudo dos mecanismos de ação do peptídeo Ac2-26 e da Piplartina nas células endoteliais de veias umbilicais humanas (HUVEC) ativadas pelo lipopolissacarídeo
(Universidade Estadual Paulista (Unesp), 2018-06-21)
Os avanços recentes nos mecanismos de inflamação e a descoberta de vários mediadores endógenos anti-inflamatórios levaram a novas investigações sobre as possibilidades terapêuticas. A demonstração, em estudos científicos, ...
Análisis del gen que codifica para el péptido lunasina
(2018-11-13)
RESUMEN: Se ha sugerido que el consumo de alimentos ricos en soya puede contribuir a disminuir el índice de cáncer de mama, próstata y colon en ciudades como China y Japón. Esto ha despertado el interés para la búsqueda ...
Determinación y caracterización de las regiones de unión de PfRON4 a eritrocitos y hepatocitos humanos
(Universidad Nacional de ColombiaBogotá - Medicina - Maestría en BioquímicaFacultad de MedicinaBogotá, ColombiaUniversidad Nacional de Colombia - Sede Bogotá, 2023-01-17)
Plasmodium falciparum durante su ciclo de vida, expresa una amplia gama de proteínas
entre las que se destaca la proteína del cuello de las roptrias 4 (PfRON4). Este es un
candidato promisorio a vacuna, ya que se expresa ...
Posibles uniones entre proteínas relacionadas con la vía PPARγ – NFκB y proteínas no estructurales de rotavirus
(Universidad Nacional de ColombiaBogotá - Ciencias - Doctorado en BiotecnologíaInstituto de Biotecnología (IBUN)Facultad de CienciasBogotá, ColombiaUniversidad Nacional de Colombia - Sede Bogotá, 2019)
Rotavirus es un virus perteneciente a la familia Reoviridae, icosaédrico sin envoltura; su cápside está constituida por tres capas: externa, media e interna. Mide aproximadamente 70 nm de diámetro, su genoma de 11 segmentos ...