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Effects of buthionine sulfoximine nifurtimox and benznidazole upon trypanothione and metallothionein proteins in Trypanosoma cruzi
(Society of Biology of Chile, 2004)
Proteins rich in sulfhydryl groups, such as metallothionein, are present in several strains of the parasite Trypanosoma cruzi, the etiological agent of Chagas' disease. Metallothionein-like protein concentrations ranged ...
Effects of buthionine sulfoximine nifurtimox and benznidazole upon trypanothione and metallothionein proteins in Trypanosoma cruzi.
(Sociedad de Biología de Chile, 2004)
Effects of buthionine sulfoximine and benznidazole upon Trypanothione and Metallothionein proteins in Trypanosoma cruzi
(BMC (Biomed Central)Grupo MalariaLondres, Inglaterra, 2022)
Buthionine sulfoximine increases the toxicity of nifurtimox and benznidazole to trypanosoma cruzi
(AMER SOC MICROBIOLOGY, 2005)
Effects of buthionine sulfoximine nifurtimox and benznidazole upon trypanothione and metallothionein proteins in trypanosoma cruzi
(SOCIEDAD DE BIOLOGIA DE CHILE, 2004)
Glutathione and trypanothione in several strains of Trypanosoma cruzi: Effect of drugs
(Elsevier Inc., 1996)
Glutathione (GSH), trypanothione (T(SH)2) and glutathionyl spermidine (GSH-SP) concentrations were determined in the Tulahuen and LQ strains and the DM 28c clone of Trypanosoma cruzi. The concentrations of GSH, T(SH)2 and ...
Buthionine sulfoximine has anti-Trypanosoma cruzi activity in a murine model of acute Chagas' disease and enhances the efficacy of nifurtimox
(AMER SOC MICROBIOLOGY, 2008)
L-Buthionine (S,R)-sulfoximine (BSO) at a dose of 220 mg/kg of body weight/day showed an anti-Trypanosoma cruzi effect in infected mice, increasing their survival rate and decreasing the parasitemias and parasite burden ...