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Segregation of brain and organizer precursors is differentially regulated by Nodal signaling at blastula stage
(Company of Biologists, 2021-02-25)
The blastula Chordin- A nd Noggin-expressing (BCNE) center comprises animal-dorsal and marginal-dorsal cells of the amphibian blastula and contains the precursors of the brain and the gastrula organizer. Previous findings ...
Notch destabilises maternal β-catenin and restricts dorsal-anterior development in Xenopus
(Company of Biologists, 2011-06)
The blastula chordin- and noggin-expressing centre (BCNE) is the predecessor of the Spemann-Mangold's organiser and alsocontains the precursors of the brain. This signalling centre comprises animal-dorsal and marginal-dorsal ...
Foxa4 favours notochord formation by inhibiting contiguous mesodermal fates and restricts anterior neural development in Xenopus embryos
(Public Library of Science, 2014-10)
In vertebrates, the embryonic dorsal midline is a crucial signalling centre that patterns the surrounding tissues during development. Members of the FoxA subfamily of transcription factors are expressed in the structures ...