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Regulatory mechanisms of cAMP levels as a multiple target for antiplatelet activity and less bleeding risk
(PERGAMON-ELSEVIER SCIENCE LTD, 2014)
Antiplatelet and Antithrombotic Activities of Non-Steroidal Anti-Inflammatory Drugs Containing an N-Acyl Hydrazone Subunit
(Mdpi Ag, 2014-02-01)
Nonsteroidal anti-inflammatory drugs (NSAIDs) 1-5 containing an N-acyl hydrazone subunit were prepared and their antiplatelet and antithrombotic activities assessed in vitro and in vivo. Compounds 1-5 inhibited the platelet ...
Relationships among Bioactive Compounds Content and the Antiplatelet and Antioxidant Activities of Six Allium Vegetable Species
(Faculty Food Technology Biotechnology, 2017-03)
Allium vegetables are widely consumed for their characteristic flavor. Additionally, their consumption may provide protection against cardiovascular disease due to their antiplatelet (AA) and antioxidant activities (AOXA). ...
Determination of antibacterial, antioxidant, antiplatelet and inhibition of cholinesterase activities from the methanolic extracts of Azorella species (Apiaceae)
(2013)
In this study, we investigated the potential antibacterial, antioxidant and anti-platelet activities and the inhibition of cholinesterase from the methanolic extracts obtained from aerial parts of the two species of Azorella: ...
Morphine and clinical outcomes in patients with ST segment elevation myocardial infarction treated with fibrinolytic and antiplatelet therapy: Insights from the TREAT trial
(Elsevier, 2022)
Background: Morphine is commonly used to relieve pain, anxiety and dyspnea in STEMI but it lowers blood pressure and delays the activity of oral antiplatelet agents. The impact of morphine on clinical outcomes remains ...
Relationships between bioactive compound content and the antiplatelet and antioxidant activities of six allium vegetable species
(2017)
Allium sp. vegetables are widely consumed for their characteristic flavour. Additionally, their consumption may provide protection against cardiovascular disease due to their antiplatelet and antioxidant activities. Although ...
Synthesis and preliminary evaluation of N-oxide derivatives for the prevention of atherothrombotic events
(Molecules, 2015)
Thrombosis is the main outcome of many cardiovascular diseases. Current treatments to prevent thrombotic events involve the long-term use of antiplatelet drugs. However, this therapy has several limitations, thereby ...
Prevalence of antiphospholipid and antiplatelet antibodies in human immunodeficiency virus (HIV)-infected Chilean patients
(WILEY, 2003)
Antiphospholipid (aPL) and antiplatelet (aPlt) antibodies, found in patients with autoimmune diseases, are also detected in infectious diseases. The purpose of this study was to examine the prevalence of these antibodies ...