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Renin-angiotensin system blockers and severe acute respiratory syndrome coronavirus 2
Severe acute respiratory syndrome coronavirus 2, which is responsible for the current coronavirus
disease 2019 pandemic, uses angiotensin-converting enzyme 2 as a gateway into host cells. In this
review, we summarize the ...
Inhibition of the renin-angiotensin system prevents seizures in a rat model of epilepsy
(PORTLAND PRESS LTD, 2010)
The RAS (renin angiotensin system) is classically involved in BP (blood pressure) regulation and water electrolyte balance, and in the central nervous system it has been mostly associated with homoeostatic processes, such ...
Angiotensin-(1-9) reverses experimental hypertension and cardiovascular damage by inhibition of the angiotensin converting enzyme/ang ii axis
(UNIV CATOLICA DE VALPARAISO, 2014)
Background: Little is known about the biological effects of angiotensin-(1-9), but available evidence shows that angiotensin-(1-9) has beneficial effects in preventing/ameliorating cardiovascular remodeling. Objective: In ...
ACE2-angiotensin-(1-7)-Mas axis in renal ischaemia/reperfusion injury in rats
(Portland Press Ltd, 2010-11-01)
AngII (angiotensin II), ACE (angiotensin I-converting enzyme) and the AT(1) receptor (AngII type I receptor) are associated with the inflammatory process and microvascular dysfunction of AKI (acute kidney injury) induced ...
New mass spectrometric assay for angiotensin-converting enzyme 2 activity
(Lippincott Williams & WilkinsPhiladelphiaEUA, 2006)
Novel players in cardioprotection: Insulin like growth factor-1, angiotensin-(1-7) and angiotensin-(1-9)
(Elsevier, 2015)
Insulin-like growth factor-1, angiotensin-(1-7) and angiotensin-(1-9) have been proposed to be important mediators in cardioprotection. A large body of evidence indicates that insulin like growth factor-1 has pleotropic ...
Aerobic Exercise Training-Induced Left Ventricular Hypertrophy Involves Regulatory MicroRNAs, Decreased Angiotensin-Converting Enzyme-Angiotensin II, and Synergistic Regulation of Angiotensin-Converting Enzyme 2-Angiotensin (1-7)
(LIPPINCOTT WILLIAMS & WILKINS, 2011)
Aerobic exercise training leads to a physiological, nonpathological left ventricular hypertrophy; however, the underlying biochemical and molecular mechanisms of physiological left ventricular hypertrophy are unknown. The ...
TRPC3 participates in angiotensin II type 1 receptor-dependent stress-induced slow increase in intracellular Ca2+ concentration in mouse cardiomyocytes
(Springer Tokyo, 2017-01)
When a cardiac muscle is held in a stretched position, its [Ca2+] transient increases slowly over several minutes in a process known as stress-induced slow increase in intracellular Ca2+ concentration ([Ca2+]i) (SSC). ...