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Characteristics, properties, and functionality of fetal membranes: An overlooked area in the field of parturition
(2018-01-01)
Throughout gestation, fetal membranes, also known as placental or amniochorion membranes, surround, and protect the fetus. Although a critical component of the intrauterine cavity, neither their cellular origin in embryo ...
Inflammation, but not infection, induces EMT in human amnion epithelial cells
(2020-10-01)
A non-reversible state of epithelial to mesenchymal transition (EMT) at term accumulates proinflammatory mesenchymal cells and predisposes fetal membrane to weakening prior to delivery at term. We investigated the induction ...
Avaliação de mediadores da resposta inflamatória na interface materno-fetal: Estudo in vitro de infecção bacteriana, isolada ou em combinação com Mycoplasma hominis, em células amnióticas epiteliais imortalizadas
(Universidade Estadual Paulista (Unesp), 2022-11-21)
To evaluate the mediators of the inflammatory response, in an in vitro model, of immortalized epithelial amniotic cells (hFM-AECs) challenged by different bacterial species, alone and in combinations with Mycoplasma hominis, ...
Treatment of chronic spinal cord injury in dogs using amniotic membrane-derived stem cells: Preliminary results
(2021-01-01)
Introduction: Intervertebral disc diseases (IVDD) represent the majority of neurological attendance and responsible for the most cases of paralysis in dogs. Treatments currently used do not show satisfactory results in ...
Produção de citocinas inflamatórias e indução da transição epitelial-mesenquimal de células amnióticas no cenário de infecção polimicrobiana
(Universidade Estadual Paulista (Unesp), 2022-09-14)
Introdução: O parto pré-termo espontâneo (PP) é considerado um dos principais problemas da clínica obstétrica e tem como uma das principais causas associada a infecção polibacteriana e consequente inflamação dos tecidos ...
Stem cells and COVID-19: are the human amniotic cells a new hope for therapies against the SARS-CoV-2 virus?
(Springer, 2021-03)
A new coronavirus respiratory disease (COVID-19) caused by the SARS-CoV-2 virus, surprised the entire world, producing social, economic, and health problems. The COVID-19 triggers a lung infection with a multiple proinflammatory ...