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Heteroleptic tris-chelate ruthenium(II) complexes of N,N-disubstituted-N '-acylthioureas: Synthesis, structural studies, cytotoxic activity and confocal microscopy studies
(Elsevier B.V., 2017-04-18)
Ruthenium complexes have been assessed as anti-tumor agents against cancer cells. In this project, new heteroleptic rutheniuM(II) complexes with general formulae [Ru(L)(bipy)(dppb)](PF6) (where L = N,N-disubstituted-N'-a ...
Structure/activity of PtII/N,N-Disubstituted-N’-acylthiourea complexes: Anti-tumor and anti-mycobacterium tuberculosis activities
(2018-06-01)
The syntheses, characterization, cytotoxicity against tumor cells and anti-Mycobacterium tuberculosis activity assays of PtII/PPh3/N,N-disubstituted-N’-acylthioureas complexes with general formulae [Pt(PPh3)2(L)]PF6, PPh3 ...
The trans-[Ru(PPh3)(2)(N,N-dimethyl-N '-thiophenylthioureato-k(2)O,S)(bipy)] PF6 complex has pro-apoptotic effects on triple negative breast cancer cells and presents low toxicity in vivo
(Elsevier B.V., 2018-09-01)
Triple negative breast cancer (TNBC) is a heterogeneous subtype of breast tumors that does not exhibit the expression of estrogen and progesterone receptors, neither the amplification of the human epidermal growth factor ...
Synthesis, characterization, and crystal structure of Ni(II) and Cu(II) complexes with N-furoyl-N',N'-diethylthiourea: antifungal activity
(Taylor and FrancisColchester, 2011-08)
The complexes cis-bis(N-furoyl-N′,N′-diethylthioureato-k 2O,S)nickel(II) and cis-bis(N-furoyl-N′,N′-diethylthioureato-k 2O,S)copper(II) were prepared by the reaction of metal acetate with the corresponding acylthiourea ...
Propriedades citotóxicas de complexos de Cu(I)-Trifenilfosfina com ligantes aciltioureias ou naftoquinonas
(Universidade Federal de São CarlosUFSCarPrograma de Pós-Graduação em Química - PPGQCâmpus São Carlos, 2021-07-26)
In this work, the synthesis, characterization, and evaluation of the cytotoxic activity of sixteen Cu(I)/Triphenylphosphine complexes containing the acylthiourea or naphthoquinones ligands are presented. The complexes were ...
Palladium(II)/N,N-disubstituted-N′-acylthioureas complexes as anti-Mycobacterium tuberculosis and anti-Trypanosoma cruzi agents
(2017-01-01)
The new complexes of Pd(II) with N,N-disubstituted-N′-acylthioureas:[(1) [Pd(dppf)(N,N-dimethyl-N′-benzoylthioureato-k2O,S)]PF6, (2) [Pd(dppf)(N,N-diethyl-N′-benzoylthioureato-k2O,S)]PF6, (3) [Pd(dppf)(N,N-dibuthyl-N′-be ...
Synthesis, Characterization and Antitumor Activity of Copper (II) Complexes, [CuL2] [HL = N,N-Diethyl-N’-(R-Benzoyl) Thiourea (R=H, o-Cl and p-NO2)]
(2005)
The copper (II) complexes (CuL(2)) were prepared by reaction of Cu(CH(3)COO)(2) with the corresponding derivatives of acylthioureas in a Cu:HL molar ratio of 1:2. Acylthiourea ligands, N,N-diethyl-N'-(R-benzoyl) thiourea ...
Synthesis, Characterization and Antitumor Activity of Copper (II) Complexes, [CuL2] [HL = N,N-Diethyl-N’-(R-Benzoyl) Thiourea (R=H, o-Cl and p-NO2)]
(2005)
The copper (II) complexes (CuL(2)) were prepared by reaction of Cu(CH(3)COO)(2) with the corresponding derivatives of acylthioureas in a Cu:HL molar ratio of 1:2. Acylthiourea ligands, N,N-diethyl-N'-(R-benzoyl) thiourea ...
Estudo de complexos metálicos de RuII, NiII, PdII e PtII com ligantes aciltioureias: atividade citotóxica e interação com biomoléculas
(Universidade Federal de São CarlosUFSCarPrograma de Pós-Graduação em Química - PPGQCâmpus São Carlos, 2019-12-20)
In this work, two series of phosphine complexes containing acylthiourea ligands were synthesized, characterizatied and evaluatied of the cytotoxic activities. The first series of compounds was composed of complexes with ...
Synthesis, characterization and antitumor activity of copper(II) complexes, [CuL2] [HL1-3=N,N-diethyl-N '-(R-benzoyl)thiourea (R=H, o-Cl and p-NO2)]
(2005)
The copper (II) complexes (CuL(2)) were prepared by reaction of Cu(CH(3)COO)(2) with the corresponding derivatives of acylthioureas in a Cu:HL molar ratio of 1:2. Acylthiourea ligands, N,N-diethyl-N'-(R-benzoyl) thiourea ...