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Efeito da rutina sobre a atividade da adenosina deaminase em ratos diabéticos
(Universidade Federal de Santa MariaBRFarmáciaUFSMPrograma de Pós-Graduação em Ciências Farmacêuticas, 2012-07-12)
Diabetes mellitus (DM) is a metabolic disorder of multiple etiology characterized by chronic hyperglycemia resulting from deficiency of insulin production and/or action. This state of hyperglycemia may cause a variety of ...
Adenosine deaminase activity as a biochemical marker of inflammatory response in goats infected by caprine arthritis-encephalitis virus
(Elsevier B.V., 2012-11-01)
Caprine arthritis-encephalitis virus (CAEV) is a lentivirus that causes a chronic and degenerative arthritis and is associated with important economic losses. Adenosine deaminase (ADA) levels increase in some human infectious ...
Adenosine deaminase activity as a biochemical marker of inflammatory response in goats infected by caprine arthritis-encephalitis virus
(Elsevier B.V., 2012-11-01)
Caprine arthritis-encephalitis virus (CAEV) is a lentivirus that causes a chronic and degenerative arthritis and is associated with important economic losses. Adenosine deaminase (ADA) levels increase in some human infectious ...
Translocation capture sequencing: A method for high throughput mapping of chromosomal rearrangements
(ELSEVIER SCIENCE BVAMSTERDAM, 2012)
Chromosomal translocations require formation and joining of DNA double strand breaks (DSBs). These events disrupt the integrity of the genome and are involved in producing leukemias, lymphomas and sarcomas. Translocations ...
TACI mutations and impaired B-cell function in subjects with CVID and healthy heterozygotes
(Elsevier, 2012-12-11)
Mutations in the gene coding for the transmembrane activator and calcium-modulating cyclophilin ligand interactor (TACI) are found in 8% to 10% of subjects with common variable immunodeficiency (CVID). Although heterozygous ...
Sevoflurane: Its action on heme metabolism and phase I drug metabolizing system
(C M B Association, 2009-12)
Acute attacks of porphyria are most commonly precipitated by events that decrease heme concentrations. Enzyme inducing-drugs are the most important triggering factors, particularly in relation to anaesthesia. We have ...
Effect of perinatal asphyxia on tuberomammillary nucleus neuronal density and object recognition memory: A possible role for histamine?
(Elsevier, 2016)
Perinatal asphyxia (PA) is associated with long-term neuronal damage and cognitive deficits in adulthood, such as learning and memory disabilities. After PA, specific brain regions are compromised, including neocortex, ...
An odd case of heteroallelic Acute Intermittent Porphyria in the Argentinean Population
(C M B Assoc, 2013-03)
AIP is an acute liver disorder caused by a deficiency of porphobilinogen deaminase (PBGD) characterized by neuroabdominal symptoms. It is an autosomal dominant disease. However, homozygous dominant AIP (HD-AIP) have been ...
MSH6- or PMS2-deficiency causes re-replication in DT40 B cells, but it has little effect on immunoglobulin gene conversion or on repair of AID-generated uracils
(Oxford University Press, 2013-03)
The mammalian antibody repertoire is shaped by somatic hypermutation (SHM) and class switch recombination (CSR) of the immunoglobulin (Ig) loci of B lymphocytes. SHM and CSR are triggered by non-canonical, error-prone ...